Towards societal alignment in the governance of human germline genome editing in the Netherlands
Bibliographic Data
| ID | 15735973 |
|---|---|
| Authors | Freek H van der Weij (Rathenau Instituut), Esther A M Bührman (0009-0000-5502-6791, Vrije Universiteit Amsterdam, corresponding author), Carla van El (0000-0003-2201-2320, Vrije Universiteit Amsterdam), Danielle Arets (Fontys University of Applied Sciences), James Kenneth Timmis (0000-0002-7773-0859, University of Freiburg), Sophie J van Baalen (Netherlands Organisation for Applied Scientific Research) |
| Year | 2025 |
| Volume | 13 |
| Issue | 1 |
| Publication date | 2025-12-19 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Responsible Innovation (JOURNAL) |
| Journal identifiers | ISSN: 2329-9037 • E-ISSN: 2329-9460 |
| Publisher | Taylor & Francis (PUBLISHER • GB) |
| DOI | 10.1080/23299460.2025.2587982 |
| OpenAlex | W4417500588 |
| Language | EN |
| References cited | 27 |
Although international consensus exists among scientists that clinical application of human germline genome editing (HGGE) should not occur in the near future, the Dutch parliament is considering significantly expanding HGGE research options. Because HGGE policy determines medical practice and potentially the lives of future generations, it is crucial that public values are safeguarded in pertinent decisions. This study applies the governance ecosystem model and anticipatory governance to provide (i) insight into the HGGE governance ecosystem in the Netherlands, and (ii) recommendations to improve societal alignment. We identify gaps in foresight and engagement activities, and a suboptimal integration of public values. We propose interdisciplinary co-creation of future scenarios, recurrent mixed-method studies, public engagement in funding requirements and transparent policy evaluation to improve societal alignment in HGGE governance. The paper demonstrates the synergy of the governance ecosystem model and anticipatory governance when developing recommendations for societal alignment
Corporate governance · Deliberation · Futures studies · Germline · Parliament · Public engagement · Public participation · Public policy · Responsible Research and Innovation · CRISPR and Genetic Engineering · Genetically Modified Organisms Research · Genomics and Rare Diseases
Technology and the Virtues
Exploring Techno-Moral Change
How to fulfill the expert role in public dialogue
Introducing the dilemma of societal alignment for inclusive and responsible research and innovation
Changing Social Representations and Agenda Interactions of Gene Editing After Crises
Using thematic analysis in psychology
Understanding 'anticipatory governance
| Citation velocity | historical |
|---|---|
| Highly cited | No |