Effect of serum lead on salivary visfatin levels in periodontitis patients using smoke or smokeless form of tobacco

To evaluate effect of serum lead on salivary visfatin levels in periodontitis patients using smoke and smokeless form of tobacco. A total of 60 male patients with generalized periodontitis stage II grade B and Grade C were selected for the study. Patients aged 30–65 years were assigned into two groups (30 subjects – Smoking tobacco group, 30 subjects – Smokeless tobacco group). Saliva samples were collected for analyses of visfatin and blood samples were collected for serum lead level analysis. Quantitative variables were compared using mean values and qualitative variables using proportions. There was statistically significant difference with (p value =0.025) mean increase in Probing pocket depth scores and (p value =0.017) in mean increase in Clinical attachment loss scores among Smokeless form of tobacco users. Mean serum Lead level was significantly high among smoke form (0.0107 + 0.007). Mean salivary visfatin level was significantly high among smoke form group (2.588±1.64). A significant correlation was found between serum Lead and Visfatin among smokeless form of tobacco users. Mean serum lead and salivary visfatin levels were statistically highly significant among the smoke form of tobacco group

Environmental health · Periodontitis · Saliva · Significant difference · Smoke · Smokeless tobacco · Tobacco smoke · Tobacco use · Chemistry · Dentistry · Medicine · Oral Health Pathology and Treatment · Oral microbiology and periodontitis research · S100 Proteins and Annexins · Gastroenterology · Internal Medicine · Physiology

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