Handling keloid and hypertrophic scars by long-pulsed Nd

Background and objectives: Keloids and HTs appear to have an abundant healing response that sets a challenge for physicians. Patients and methods: Patients with keloids and HTs were handled by a long-pulsed 1064 nm Nd: YAG laser every 4 weeks for five sessions. The number of patients was twenty. The scars were rated by VSS, consisting of 4 ingredients: vascularity, pigmentation, pliability, and height. Moreover, histopathological assessment by hematoxylin and eosin stain and Masson trichrome stain. After 6 months of finishing the treatment, the lesion was estimated to evaluate the recurrence rate. Results: According to VSS, there was a considerable improvement in vascularity, pigmentation, pliability, and height after the treatment than before the treatment. The score of the scar assessment dropped off from 9.40 to 3.75 after treatment. Hematoxylin and eosin staining and Elastica Masson-Goldner staining appeared to change the structure of the tissue collagen. Collagen bundles lost their whirl structure, and the thickness of the collagen layer decreased. The Wall of blood vessels was thinner, and the number of blood vessels was decreased. Conclusion: The treatment of keloids and HTs showed great results with a long-pulsed Nd-YAG laser

Eosin · H&E stain · Hypertrophic scars · Immunohistochemistry · Keloid · Laser · Lesion · Masson's trichrome stain · Pathology · Port-wine stain · Scars · Stain · Staining · Trichrome · Trichrome stain · Vascularity · Dermatologic Treatments and Research · Laser Applications in Dentistry and Medicine · Medicine · Oropharyngeal Anatomy and Pathologies