Place of Uterine Artery and Umbilical Artery Doppler in Prediction of Hypertensive Disorders (Pre-Eclampsia) Among Pregnant Women at a Resource Poor Setting

Background: Uterine and umbilical artery Doppler velocimetry have shown promise but the results of previous studies have not been conclusive/poor methodologies. Aim: To determine the predictive value of uterine and umbilical artery Doppler velocimetry for pre-eclampsia and pregnancy outcomes. Methods: A comparative study among 100 women who attended ante natal clinic in the hospital within the study period who has high risk for development of pre-eclampsia. The peak systolic velocity, end-diastolic velocity, Resistivity index, Pulsatility index and S/D ratio of the uterine and umbilical arteries were studied at 18-20 weeks and 36-37 weeks. sociodemographic data were recorded. Data were analysed using SPSS (version 26, Chicago11, USA). P value of ≤ 0.05 was significant. Results: Resistivity/Pulsatility indices at 18-20 weeks are better predictors of preeclampsia as against EDV at 36-37 weeks. Pregnant women at 18-20 weeks gestational showed that only mean RI (≈ 0.53 0.02) of the umbilical artery was associated with adverse outcome (p = 0.009). However, at 36-37 weeks, the mean uterine artery EDV of 14.69 2.04 was associated with adverse outcome (p = 0.001). Conclusion Adverse pregnancy outcome at n18-20 weeks was associated with resistivity index while EDV is more associated with adverse outcomes at 36-37 weeks

Biology · Cardiology · Eclampsia · Fetus · Gestation · Obstetrics · Pregnancy · Umbilical artery · Uterine artery · Birth, Development, and Health · Global Maternal and Child Health · Medicine · Pregnancy and preeclampsia studies

• Maternal mortality

  Open Access•Carine Ronsmans, Warren Graham et al.•The Lancet•2006

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