Effect of licorice (Glycyrrhiza glabra) on peptic ulcer in rats
Bibliographic Data
| ID | 15798264 |
|---|---|
| Authors | Ahmed Ali Ameen (Helwan University, corresponding author), Hany El-Masry (Helwan University, corresponding author), Hany Gaber El-Masry, Mounira Yehia Mohamed Hassen El Bashatly (Helwan University, corresponding author) |
| Year | 2022 |
| Pages | 12173-12183 |
| Publication date | 2022-08-17 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Health Sciences (JOURNAL) |
| Journal identifiers | ISSN: 2550-696X • E-ISSN: 2550-6978 |
| Publisher | Universidad Tecnica de Manabi (PUBLISHER • EC) |
| DOI | 10.53730/ijhs.v6ns4.11829 |
| OpenAlex | W4292262805 |
| Language | EN |
| References cited | 2 |
A peptic ulcer is sore on the lining of the stomach or duodenum; the two most common types of peptic ulcer are celled gastric ulcer and duodenum ulcer. Peptic ulcer are found to be due to an imbalance between aggressive factor such as hydrochloric acid (HCL), pepsin and refluxed bile. As the current study aimed to investigate the protective effect of Licorice against peptic ulcer.Thirty male Wistar albino rats were randomly divided into five groups (n = 6) as follow; -ve control group fed basal diet, +ve control group fed basal diet and injected with a single dose of Ranitidine (20mg/kg/day, bw, p.o.) (7 days). Groups 3-5 fed licorice with 1 ml. once a week, 1 ml. twice a week, 1 ml. three times a week respectively. Results revealed that licorice caused a significant decrease in blood cholesterol level, TG, LDL, AST, ALT, urea nitrogen, uric acid, creatinine, uric acid, albumin and VLDL. In addition, licorice caused a significant increase in HDL and PH, especially in group 5 which fed 3 ml. compared to +ve control group
Albumin · Basal (medicine · Duodenum · Glycyrrhiza · Pepsin · Peptic ulcer · Ranitidine · Stomach · Uric acid · Chemistry · Helicobacter pylori-related gastroenterology studies · Hormonal Regulation and Hypertension · Medicine · Pharmacological Effects of Natural Compounds · Biochemistry · Gastroenterology · Internal Medicine
| Highly cited | No |
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