Screening of AmpC-Family genes among Pseudomonas aeruginosa isolated from burn patients in Najaf City, Iraq
Bibliographic Data
| ID | 15798907 |
|---|---|
| Authors | Salam Ali Abd Al-Absawe (University of Kufa, corresponding author), Nabil Salim Saaid Tuwaij (0000-0001-7130-6574, University of Kufa) |
| Year | 2022 |
| Pages | 3547-3555 |
| Publication date | 2022-09-08 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Health Sciences (JOURNAL) |
| Journal identifiers | ISSN: 2550-696X • E-ISSN: 2550-6978 |
| Publisher | Universidad Tecnica de Manabi (PUBLISHER • EC) |
| DOI | 10.53730/ijhs.v6ns7.12572 |
| OpenAlex | W4295095568 |
| Language | EN |
| References cited | 5 |
Burn patients are at risk of severe infections caused by pseudomonas aeruginosa due to their immunosuppressive conditions. A one mechanism of resistance in this pathogen by AmpC beta-lactamases, therefore this study included molecular screening AmpC family genes among isolates of P. aeruginosa. The present work was conducted in Al-Sadr Medical City, and burns unit center as well as some chief clinical laboratories in Al-Najaf City period December 2021 to March 2022. An entirety of 68 patients were checked to recognize P. aeruginosa isolates. Bacterial growth were 59 (86.76%), as following 12(17.64%), 47 (69.11%) and 9 (13.23%) for gram-positive bacteria, gram-negative and non- growth respectively .Results recorded 32(54.23%) of P. aeruginosa isolates. At same respect, the percentage of P. aeruginosa isolates in women were 20(33.89%) compared with 12(20.33%) in male. Results showed 20(62.5%) of isolates were resistance to piperacillin-tazobactam, , with a MIC of 128 μg/ml, Also data in table (2) showed that 32(100%) resistance to cefazoline antibiotic at MIC of 64 μg/ml. Whereas, the bacterial isolates showed less resistance to ceftazidime and cefepime, as the resistance ratios reached 21(65.62%) and 19(59.37%) respectively.the results showed that 20(62.5%) were resistant to imipenem while 19(59.37) and 18(56.25) were resistance gentamycin and amikacin respectively
Amikacin · Antibiotic resistance · Antibiotics · Bacteria · Biology · Cefepime · Ceftazidime · Ciprofloxacin · Imipenem · Piperacillin · Pseudomonas aeruginosa · Tazobactam · Diverse Scientific Research Studies · Healthcare and Environmental Waste Management · Medicine · Pharmacology and Nanomedicine Research · Microbiology
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| Highly cited | No |
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