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Correlation between alveolar-arterial oxygen tension difference gradient baseline with spirometry test in severe coronavirus disease 2019 (Covid-19)

Bibliographic Data

ID15799233
AuthorsIda Bagus Janantara Wirakusuma (Udayana University, corresponding author), I Ketut Agus Somia (0000-0001-6339-3401, Udayana University, corresponding author), Ni Luh Putu Eka Arisanti (0000-0003-1702-3906, Udayana University, corresponding author), Ida Bagus Ngurah (Udayana University, corresponding author), Ida Ayu Jasminarti Dwi Kusumawardani (0000-0002-2716-5222, Udayana University, corresponding author), Ni Wayan Candrawati (0000-0002-6634-0994, Udayana University, corresponding author), I Gusti Ngurah Bagus Artana (Udayana University, corresponding author)
Year2022
Pages2578-2588
Publication date2022-09-25
Open AccessYes
TypeARTICLE
VenueInternational Journal of Health Sciences (JOURNAL)
Journal identifiersISSN: 2550-696X • E-ISSN: 2550-6978
PublisherUniversidad Tecnica de Manabi (PUBLISHER • EC)
DOI10.53730/ijhs.v6ns9.12986
OpenAlexW4297054353
LanguageEN
References cited3

Alveolar-arterial Oxygen Tension Differences are one of the oxygenations that can increase SARS-CoV-2 virus infection. Based on this, the researchers wanted to assess the relationship between the baseline AaDO2 gradient and spirometry tests in severe COVID-19 survivors. This research is an observational analytic study with a cross-sectional design. The analysis was carried out in bivariate and multivariate tests assisted by using SPSS 26. The subjects who participated in the study were 80 people. Subjects with AaDO2 values > 39.4 mmHg 70% (n=56), median AaDO2 gradient was 60.45 (2.75 - 548.2 mmHg). The relationship between baseline AaDO2 analysis and spirometry results showed that it was associated with FVC and FEF25-75% results, respectively (PR) 18.6 (95% CI 3.978-87.401 p = <0.001) and (PR) 7.7 (95% CI 1.606-3.724 p = 0.011) and no significant with FEV1 and FEV1/FVC values. This study concludes a relationship between a high baseline AaDO2 gradient with FVC and FEF values of 25-75% in severe adult COVID-19 survivors. There was no relationship between a high baseline AaDO2 gradient and FEV1 and FEV1/FVC values

Arterial oxygen tension · Asthma · Cardiology · Coronavirus disease 2019 (COVID-19 · Disease · Lung · Multivariate analysis · Observational study · Oxygen · Oxygen tension · Spirometry · Chemistry · COVID-19 diagnosis using AI · Diverse Scientific Research Studies · Medicine · Public Health and Nutrition · Internal Medicine

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