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Instability of Global Burden of Disease Estimates of Deaths and Disability-Adjusted Life-Years From Major Risk Factors

A Meta-Epidemiological Analysis

Bibliographic Data

ID15808448
AuthorsEmmanuel A Zavalis (0000-0001-6205-1362, Karolinska Institutet), Angelo Maria Pezzullo (0000-0002-8252-4654, Meta-Research Innovation Center at Stanford, Stanford University, Stanford, California), John P A Ioannidis (0000-0003-3118-6859, Innovative Research (United States), corresponding author)
Year2026
Volume7
Issue3
Pagese260108-e260108
Publication date2026-03-13
Open AccessYes
TypeARTICLE
VenueJAMA Health Forum (JOURNAL)
Journal identifiersISSN: 2689-0186 • E-ISSN: 2689-0186
PublisherAmerican Medical Association (PUBLISHER • US)
DOI10.1001/jamahealthforum.2026.0108
PMID41823958
OpenAlexW7135222004
LanguageEN
References cited25

This meta-epidemiological assessment indicates that GBD estimates are substantially unstable, particularly for behavioral risks, making them unlikely to simply reflect genuine changes over time, and warranting caution in interpretation

Burden of disease · Disease · Disease burden · Estimation · Population · Risk assessment · Cerebral Palsy and Movement Disorders · Health disparities and outcomes · Health Systems, Economic Evaluations, Quality of Life

  • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021

    Open Access•Michael Brauer, Gregory A Roth et al.•The Lancet•2024

  • Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013

    Open Access•Mohammad H Forouzanfar, Lily Alexander et al.•The Lancet•2015

  • Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017

    Open Access•Jeffrey D Stanaway, Ashkan Afshin et al.•The Lancet•2018

  • Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2016

    Open Access•Emmanuela Gakidou, Ashkan Afshin et al.•The Lancet•2017

  • The Global Burden of Disease Study at 30 years

    Open Access•Christopher J L Murray•Nature Medicine•2022

  • Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015

    Open Access•Mohammad H Forouzanfar, Ashkan Afshin et al.•The Lancet•2016

  • The PRISMA 2020 statement

    Open Access•Matthew J Page, Joanne E McKenzie et al.•BMJ•2021

  • Global burden of 87 risk factors in 204 countries and territories, 1990–2019

    Open Access•Christopher J L Murray, Aleksandr Y Aravkin et al.•The Lancet•2020

  • A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010

    Open Access•Stephen S Lim, Theo Vos et al.•The Lancet•2012

  • Completeness and quality of low back pain prevalence data in the Global Burden of Disease Study 2017

    Open Access•Mamata Tamrakar, Priti Kharel et al.•BMJ Global Health•2021

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