Trend analysis of leprosy indicators in a hyperendemic Brazilian state, 2001–2015

Bibliographic Data

ID16780293
AuthorsJefferson De Jesus Silva Anchieta (0000-0001-6139-6983, Secretaria da Saúde), Léa Márcia Melo da Costa (0000-0003-0607-8506, Secretaria da Saúde), Ludmila Caliman Campos (0000-0002-6675-4433, Secretaria da Saúde), Maurício Dos Remédios Vieira (0000-0001-8276-8846, Secretaria da Saúde), Osvaldina Silva Mota (0000-0001-8299-9249, Secretaria da Saúde), Otaliba Libânio De Morais Neto (0000-0002-3786-318X, Universidade Federal de Goiás), Marta Rovery De Souza (0000-0001-6910-843X, Universidade Federal de Goiás), Rafael Alves Guimarães (0000-0001-5171-7958, Universidade Federal de Goiás)
Year2019
Volume53
Pages61
Publication date2019-08-09
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueRevista de Saúde Pública (JOURNAL)
Journal identifiersISSN: 0034-8910 • E-ISSN: 0034-8910
PublisherUniversidade de São Paulo. Agência de Bibliotecas e Coleções Digitais (PUBLISHER)
DOI10.11606/s1518-8787.2019053000752
PMID31390430
OpenAlexW2962994127
LanguageEN
Citations received1
References cited5

OBJECTIVE: To analyze the temporal trend of leprosy indicators in a hyperendemic state of Brazil, from 2001–2015. METHODS:This is a time-series study of leprosy indicators in the state of Maranhão, Northeastern region of Brazil. The study used data from the Brazilian National System of Reportable Diseases, for the period between 2001 and 2015. The following indicators were evaluated: (i) detection coefficient in the general population; (ii) detection coefficient in people under 15 years old; (iii) rate of cases with grade 2 physical disability in the diagnosis; (iv) rate of examined contacts, and (v) proportion of healing . The Prais-Winsten regression model was used for trend analysis. Analyses were performed for the state and by each health region. RESULTS: 77,697 leprosy cases were analyzed in the general population and 7,599 in individuals under 15 years old. The detection coefficient in the general population ranged from 80.7/100 thousand inhabitants in 2001 to 51.2/100 thousand inhabitants in 2015. The coefficient in the general population presented a downward trend (annual percentage variation [APV] = -2.98; 95%CI -4.15– -1.79). For the population under 15 years old, the rate was 24.9/100 thousand inhabitants in 2001, and 19.9/100 thousand inhabitants in 2015, with downward trend (APV = -3.07; 95%CI -4.95– -1.15). It was observed upward trend in rate of contacts examined (APV = 2.35; 95%CI 0.58–4.15) and rate of cases with grade 2 disability (APV = 2.19; 95%CI 0.23–4.19). Stationary trend was observed in the proportion of healing (APV = -0.10; 95%CI -0.50–0.30). Regional differences were found in the performance of the indicators. CONCLUSIONS: A downward trend for the detection coefficients in the general population and in individuals under 15 years old was found in Maranhão. Despite this result, the rates are still very high, demanding efforts from all spheres of public administration and health professionals to reduce the burden of the disease in the state

Geography · Leprosy · Population · Regression analysis · Statistics · Trend analysis · Demography · Health Education and Validation · Leprosy Research and Treatment · Maternal and Neonatal Healthcare · Mathematics · Medicine