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Factors associated with fetal macrosomia

Bibliographic Data

ID16780428
AuthorsVanessa Agudelo-Espitia (0000-0003-3561-286X, EIA University), Beatriz Elena Parra-Sosa (0000-0001-8808-7515, Universidad de Antioquia), Sandra Lucía Restrepo-Mesa (0000-0002-3938-4238, Universidad de Antioquia)
Year2019
Volume53
Pages100
Publication date2019-11-21
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueRevista de Saúde Pública (JOURNAL)
Journal identifiersISSN: 0034-8910 • E-ISSN: 0034-8910
PublisherUniversidade de São Paulo. Agência de Bibliotecas e Coleções Digitais (PUBLISHER)
DOI10.11606/s1518-8787.2019053001269
PMID31800911
OpenAlexW2989703543
LanguageEN
Citations received1
References cited4

OBJECTIVE: To evaluate the clinical factors, as well as weight gain, in a group of pregnant women, associating them with fetal macrosomia in a public institution in Antioquia, Colombia, from 2010-2017. METHODS: A case-control study, using secondary information registries. Cases were defined using newborn weight of ≥ 4000g, while controls were defined as newborn weight between 3000– 3999g. A proportion ratio (PR) was established to evaluate factors associated with macrosomia, and a generalized linear model (GLM) of Poisson regression with robust variance was used to evaluate the aspects that best explained macrosomia in the neonate. RESULTS: 122 pregnant women participated in the study, of which 611 were cases and 61 were controls. Of the participants, 44.3% had pre-pregnancy overweight and 48.4% had excess gestational weight gain. Statistically significant differences were found between the groups in the following variables: pre-pregnancy BMI (p = 0.004), gestational weight gain (p = 0.000), gestational diabetes (p = 0.000), and type of delivery (p = 0.004). According to the regression model, a macrosomic newborn is 3.5 times more likely in women with excessive gestational weight gain (95%CI 1.78-7.18) and twice more likely in women who have gestational diabetes (95%CI 1.51-2.76). Of women with pre-pregnancy excess weight, 63% had excess gestational weight gain. CONCLUSIONS: Within this cohort, pre-pregnancy BMI, excess weight gain in pregnancy, and the presence of gestational diabetes were associated with an increased risk of neonatal macrosomia. pre-pregnancy BMI and weight gain in pregnancy are modifiable risk factors that are responsive to nutrition interventions, which can minimize adverse perinatal outcomes

Birth weight · Body mass index · Body weight · Fetal macrosomia · Gestation · Gestational age · Gestational diabetes · Obstetrics · Overweight · Pregnancy · Weight gain · Cancer Risks and Factors · Gestational Diabetes Research and Management · Internal Medicine · Medicine · Pregnancy and preeclampsia studies

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  • The World's women, 1970-1990

    United Nations•The World's women, 1970-1990•1991

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Unique citing works1
Citations per year1
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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