Occupational exposure to pesticides and hematological alterations
A survey of farm residents in the South of Brazil
Bibliographic Data
| ID | 16828536 |
|---|---|
| Authors | Camila Piccoli (0000-0003-0462-557X, Fiocruz, Brasil), Cleber Cremonese (0000-0003-2700-7416, Centro Universitário da Serra Gaúcha, Brasil), Rosalina Koifman (0000-0003-4391-4542, Fiocruz, Brasil), Sergio Koifman (0000-0003-1769-3985, Fiocruz, Brasil), Carmen Freire Warden (0000-0001-7370-1842, Institute of Biomedical Research of Granada, Espanha) |
| Year | 2019 |
| Volume | 24 |
| Issue | 6 |
| Pages | 2325-2340 |
| Publication date | 2019-06-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Ciência & Saúde Coletiva (JOURNAL) |
| Journal identifiers | ISSN: 1413-8123 • E-ISSN: 1678-4561 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/1413-81232018246.13142017 |
| PMID | 31269189 |
| OpenAlex | W2953788584 |
| SciELO | S1413-81232019000602325 |
| Language | EN |
| Citations received | 2 |
| References cited | 34 |
This study sought to investigate the association of exposure to organochlorine (OC) and non-persistent pesticides with hematological parameters in an agricultural population in Southern Brazil. A cross-sectional study was conducted with a random sample of 275 farm workers and their families in Farroupilha-RS. A questionnaire was used to collect information on sociodemographic and lifestyle factors, duration, frequency and type of pesticide used, among others. Blood samples were collected and analyzed for serum concentration of 24 OC pesticides and hematological parameters. Associations were explored through linear regression, controlling for confounders. Lifetime use of chemical classes other than organophosphates and dithiocarbamates were associated with decreased number of lymphocytes, while subjects sampled in the high pesticide use season showed higher number of erythrocytes and hemoglobin level. Detectable serum levels of many OC pesticides were associated with lower counts of white blood cells, particularly eosinophils. Although mostly null associations were observed between pesticide use and hematological parameters, findings may suggest that OC pesticides could lead to hematological alterations among agricultural workers
Agriculture · Biology · Confounding · Cross-sectional study · Environmental health · Pathology · Pesticide · Population · Carcinogens and Genotoxicity Assessment · Medicine · Pesticide Exposure and Toxicity · Toxic Organic Pollutants Impact · Internal Medicine · Physiology · Toxicology
| Citations per year | 0.4 |
|---|---|
| Citation span | 2021 - 2022 (2) |
| Highly cited | No |