Analysis of the population genetic structure of Hb D‐ L os A ngeles [β121 (GH4) Glu→Gln G AA→ C AA] in D enizli, T urkey; genetic diversity, historical demography and estimation of the mutation rates based on haplotype variation
Bibliographic Data
| ID | 17701893 |
|---|---|
| Authors | Onur Öztürk (0000-0003-3404-4135, Department of Biophysics Inonu University School of Medicine Malatya Turkey, corresponding author), S Arıkan (0000-0001-7987-9078, Pamukkale University), Sanem Arikan (Department of Biophysics Pamukkale University School of Medicine Denizli Turkey), Ayfer Atalay (Department of Biophysics Pamukkale University School of Medicine Denizli Turkey), Erol Ömer Atalay (Pamukkale University) |
| Year | 2015 |
| Volume | 28 |
| Issue | 4 |
| Pages | 476-483 |
| Publication date | 2015-12-17 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Human Biology (JOURNAL) |
| Journal identifiers | ISSN: 1042-0533 • E-ISSN: 1520-6300 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajhb.22816 |
| PMID | 26680249 |
| OpenAlex | W2218056127 |
| Language | EN |
| References cited | 47 |
Our data suggest that the Hb D-Los Angeles population originated within the normal population in Denizli, Turkey. Our results support the hypothesis that the Hb D-Los Angeles mutation may have originated in the Mediterranean area, independent from other populations such as India and China. The evaluation of such data may contribute valuable information to anthropological, paleoclimatic, archaeological, and phylogeographical approaches to human biology throughout the historical period. Am. J. Hum. Biol. 28:476-483, 2016. © 2015 Wiley Periodicals, Inc
Biology · Population · Chemistry · Forensic and Genetic Research · Genetic Associations and Epidemiology · Hemoglobinopathies and Related Disorders · Medicine · Genetics · Molecular Biology
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| Highly cited | No |
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