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Greenspace and mortality in the U.K. Biobank

Longitudinal cohort analysis of socio-economic, environmental, and biomarker pathways

Bibliographic Data

ID17827165
AuthorsShiyu Wan (0000-0002-4962-360X, University of North Carolina at Chapel Hill), David Rojas‐Rueda (0000-0001-5854-2484, Colorado School of Public Health), Jules Pretty (0000-0002-3897-6581, University of Essex), Charlotte Roscoe (0000-0002-9169-6458, Brigham and Women's Hospital), Peter James (0000-0002-8447-4638, Harvard University), John S Ji (0000-0002-5002-118X, Vanke (China), corresponding author)
Year2022
Volume19
Pages101194-101194
Publication date2022-08-18
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueSSM - Population Health (JOURNAL)
Journal identifiersISSN: 2352-8273 • E-ISSN: 2352-8273
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.ssmph.2022.101194
PMID36059376
OpenAlexW4292242423
LanguageEN
Citations received6
References cited65

Exposure to natural greenspace benefits health through direct and indirect pathways: increasing physical activity, improving mental health, relieving social isolation, reducing exposure to extreme temperature, noise, and air pollution. Understanding the etiologic pathway of greenspace and health is needed. Here, we used a large cohort follow-up data from the U.K. Biobank to quantify the magnitude of behavioural factors, psychological factors, biomarkers/physiological measurements, co-morbid diseases, and environmental exposure as potential mediators in the relationship between greenspace and mortality. We estimated hazard ratios (HR) with Cox proportional hazards models, and undertook exploratory mediation analyses to quantify the relative contribution of five types of mediators. Our results indicate greenspace was strongly associated with lower mortality risks [per IQR of public greenspace (HR = 0.90 (95% CI 0.86-0.84)) and domestic gardens (HR = 0.91, (95% CI 0.88-0.94))]. The protective associations were especially pronounced among those with lower individual-level socioeconomic status or living in places with area-level deprivation. Exploratory mediation analysis detected benefits in pathways through reducing air pollution, relieving social isolation and depression, increased physical activity and time spent outdoor, better lung function (FEV1/FVC), and having higher serum vitamin D levels

Biobank · Biology · Cohort · Cohort study · Confidence interval · Environmental health · Hazard ratio · Mediation · Population · Proportional hazards model · Psychiatry · Social isolation · Socioeconomic status · Demography · Medicine · Noise Effects and Management · Psychology · Urban Green Space and Health · Urban Heat Island Mitigation · Gerontology · Internal Medicine

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Unique citing works6
Citations per year3
Citation span2024 - 2025 (2)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 6

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