Relationship between mitochondrial haplogroup and psychophysiological responses during cold exposure in a Japanese population
Bibliographic Data
| ID | 18948567 |
|---|---|
| Authors | Takayuki Nishimura (0000-0001-5791-7512, Kyushu University, corresponding author), Midori Motoi (Kyushu University), Yoshikazu Hoshi (Tokai University), Ryuichiro Kondo (Kyushu University), Shigeki Watanuki (0000-0003-4256-8828, Kyushu University) |
| Year | 2011 |
| Volume | 119 |
| Issue | 3 |
| Pages | 265-271 |
| Publication date | 2011-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Anthropological Science (JOURNAL) |
| Journal identifiers | ISSN: 0918-7960 • E-ISSN: 1348-8570 |
| Publisher | Anthropological Society of Nippon (PUBLISHER • JP) |
| DOI | 10.1537/ase.101009 |
| OpenAlex | W2030163427 |
| Language | EN |
| Citations received | 1 |
| References cited | 35 |
The purpose of this study was to investigate the genetic factors responsible for individual differences in cold tolerance. Focusing on mitochondrial haplogroup D (D4) in Japanese subjects, differences in cold tolerance between haplogroup D subjects and other haplogroup subjects were investigated. The experiment was conducted in summer (August-September). Room temperature was decreased from 27 to 10C in 30 min, and cold exposure was then maintained at 10C for 60 min. During that time, measurements were made of physiological responses, including rectal temperature, skin temperature, oxygen consumption, blood pressure, and heart rate. A subjective evaluation was also made. It was found that, under cold exposure, the decrease in rectal temperature of haplogroup D subjects was significantly less than that in other groups (P < 0.001). There was no significant main group effect for oxygen consumption or mean skin temperature. In haplogroup D subjects, the thermal comfort sensation was judged to be significant discomfort at 20 and 30 min after the start of cold stimulation (P < 0.05). From the relation of oxygen consumption to rectal temperature, it is conjectured that the rectal temperature at which increased thermogenesis starts is higher in haplogroup D subjects. This study suggests that differences in mitochondrial haplogroup are one factor in individual differences in cold tolerance in Japanese
Allele · Animal science · Biology · Blood pressure · Gene · Haplogroup · Haplotype · Heart rate · Human mitochondrial DNA haplogroup · Population · Rectal temperature · Adipose Tissue and Metabolism · Climate Change and Health Impacts · Medicine · Thermoregulation and physiological responses · Genetics · Internal Medicine
| Citations per year | 0.07 |
|---|---|
| Citation span | 2012 - 2012 (1) |
| Highly cited | No |