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The effect of increased bilirubin level on the risk of cerebral palsy

Bibliographic Data

ID19004918
AuthorsSternal Marta (Wrocław University of Environmental and Life Sciences, corresponding author), B Kwiatkowska (0000-0003-3662-1821, Wrocław University of Environmental and Life Sciences), Krzysztof Borysławski (0000-0002-6290-1192, Wrocław University of Environmental and Life Sciences), Agnieszka Tomaszewska (0000-0001-5295-9107, Wrocław University of Environmental and Life Sciences)
Year2020
Volume83
Issue2
Pages185-195
Publication date2020-06-23
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnthropological Review (JOURNAL)
Journal identifiersISSN: 1898-6773 • E-ISSN: 2083-4594
PublisherDe Gruyter Open (PUBLISHER • PL)
DOI10.2478/anre-2020-0013
OpenAlexW3037679124
LanguageEN
Citations received1
References cited17

Increased bilirubin level in blood is mentioned among the potential factors with causal effect on cerebral palsy. The objective of the study was the analysis of its effect on the risk of cerebral palsy, considering all the significant risk factors as well as division into singleton, twin, term and preterm births. The research included a group of 278 children with cerebral palsy from selected educational-therapeutic institutions in Poland. The control group consisted of data from medical records of 435 neonates born in God’s Mercy Hospital in Limanowa, Poland. The analysis considered socio-economic factors, factors associated with pregnancy and parturition as well as accompanying disturbances and diseases of the children. Constructed models of logistic regression were used in statistcal analysis. The results were presented as the odds ratio (OR) with 95% confidence interval (CI). Testing the effect of increased bilirubin level in blood showed that the increased level of bilirubin is a significant predictor of CP in the categories of all children (OR 2.52, 95% CI: 1.47–4.33), children from singleton births (OR 2.66, 95% CI: 1.55–4.57), term births (OR 2.18, 95% CI: 1.24–3.84), term singleton births (OR 2.35, 95% CI: 1.31–4.21), preterm births (4.87, 95% CI: 1.56–15.21) and preterm singleton births (OR 3.62, 95% CI: 1.24–10.58). Increased bilirubin level is an independent risk factor in the development of cerebral palsy

Bilirubin · Cerebral palsy · Confidence interval · Logistic regression · Obstetrics · Odds ratio · Physical therapy · Pregnancy · Risk factor · Singleton · Medicine · Neonatal and fetal brain pathology · Neonatal Health and Biochemistry · Neonatal Respiratory Health Research · Internal Medicine · Pediatrics

  • Maternal age as a risk factor for cerebral palsy

    Open Access•Marta Sternal, B Kwiatkowska et al.•Anthropological Review•2021

  • Paternal age and the risk of cerebral palsy

    Open Access•Marta Sternal, Sternal Marta et al.•Anthropological Review•2020

Unique citing works1
Citations per year0,2
Citation span2021 - 2021 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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