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Association Between Patient Health Questionnaire-4 Composite Score and Depression Diagnoses in a Free Clinic Setting

Pooled Cross-sectional Study

Datos Bibliográficos

ID19265508
AutoresSri Varsha Katoju (University of Florida Health, autor de correspondencia), Jessica Diana (University of Central Florida, autor de correspondencia), Elijah Moothedan (Florida Atlantic University), Avaneesh Kunta (0009-0002-5525-6997, University of Central Florida), Oliver Nguyen (0009-0005-3826-3839, University of Florida Health), Anshul Daga (0000-0003-3667-3082, University of Florida Health), Kartik Motwani (0000-0003-1893-8235, University of Florida), David Feller (University of Florida Health)
Año2026
Fecha de publicación2026-05-22
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaCommunity Mental Health Journal (JOURNAL)
Identificadores de la revistaISSN: 0010-3853 • E-ISSN: 1573-2789
EditorialSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s10597-026-01662-1
PMID42171962
OpenAlexW7162110442
IdiomaEN
Referencias citadas64

This study aimed to examine the predictive validity of the Patient Health Questionnaire-4 (PHQ-4) in identifying depression diagnoses among patients in a student-run free clinic (SRFC) setting. This pooled cross-sectional study utilized electronic health record data from the Equal Access Clinic Network, a network of SRFCs affiliated with the University of Florida. All adult patients who completed PHQ-4 screening questions between October 2015 and February 2020 and had a corresponding ICD-10 diagnostic code were included ( n = 2,498). The PHQ-4 composite score, calculated from binary responses to four mental health screening questions, served as the primary independent variable. The primary outcome was provider-diagnosed Major Depressive Disorder (MDD), defined by ICD-10 code F32.9. A multivariable logistic regression model, adjusted for age, sex, race/ethnicity, employment, and marital status, was used to evaluate the association between PHQ-4 scores and provider-diagnosed MDD. Higher PHQ-4 composite scores were significantly associated with increased odds of receiving an MDD diagnosis (adjusted OR = 2.047; 95% CI: 1.830–2.289; p

Depression (economics) · Diagnosis code · Ethnic group · Logistic regression · Major depressive disorder · Marital status · Medical diagnosis · Mental health · Odds · Odds ratio · Cancer survivorship and care · Mental Health Treatment and Access · Treatment of Major Depression

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