Association between 23 urinary VOC metabolites and cardiovascular disease among NHANES participants
Bibliographic Data
| ID | 19269663 |
|---|---|
| Authors | Lubna A Zar (0000-0003-1082-7557, Qatar University, corresponding author), Munirah Altaissan (Qatar University), Haya Rahimi (Qatar University), Rayyan Mukhtar (Qatar University), Sara Alailah (Qatar University), Hamad Almahdi (Qatar University), Abdulla Al-Kaabi (Qatar University), Rafif Abdulaziz Mahmood (Qatar University), Salma M Khaled (0000-0002-8844-3441, Qatar University), Giridhara R Babu (0000-0003-4370-8933, Qatar University) |
| Year | 2025 |
| Volume | 82 |
| Issue | 3 |
| Pages | 1355-1367 |
| Publication date | 2025-05-04 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Studies (JOURNAL) |
| Journal identifiers | ISSN: 0020-7233 • E-ISSN: 1026-7476 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/00207233.2024.2444195 |
| OpenAlex | W4405987296 |
| Language | EN |
| References cited | 28 |
This paper reports on the association between urine concentrations of Volatile Organic Compounds (UVOCs) metabolites and Cardiovascular Diseases (CVDs). This cross-sectional study uses a sample of participants from the NHANES (2017–2020). We assessed the dose association of UVOCs with CVD by running multivariable logistic regression models at the second, third and fourth quartiles. Among 2,363 participants in the National Health and Nutrition Examination Survey (NHANES) who had complete UVOC and CVD disease data, 11.9% (N = 282) had at least one cardiovascular disease event. The UVOCs of Acrolein (aOR 2.26, 95%CI 1.24–4.12 p = 0.01), Acrylamide (aOR 1.81, 95%CI 1.20–2.73, p = 0.006), 1,3-Butadiene (aOR 2.06 95%CI 1.13–3.75, p = 0.019), Propylene oxide (2.12, 95%CI 1.22–3.70, p = 0.01) in quartile-4 were associated with higher odds of CVDs. At high concentrations, metabolites of Benzene, Acrolein, Acrylonitrile, 1,3-Butadiene, and Crotonaldehyde increase the odds of developing stroke
Disease · Environmental health · National Health and Nutrition Examination Survey · Population · Urinary system · Air Quality and Health Impacts · Air Quality Monitoring and Forecasting · Climate Change and Health Impacts · Internal Medicine · Medicine
| Highly cited | No |
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