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The effect of changes in nitrate concentration in drinking water on methemoglobin levels in infants

Bibliographic Data

ID19271155
AuthorsNachman Gruener (Hebrew University of Jerusalem), Raphael Toeplitz (Hebrew University of Jerusalem)
Year1975
Volume7
Issue3
Pages161-163
Publication date1975-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueInternational Journal of Environmental Studies (JOURNAL)
Journal identifiersISSN: 0020-7233 • E-ISSN: 1026-7476
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/00207237508709688
OpenAlexW2043157458
LanguageEN
References cited6

For a five‐day period infants consuming powdered milk formula made up with tap water were exposed to water of controlled nitrate content. There was a significant rise in MetHb levels above normal in most children after the first day of exposure to high nitrate water (108 mg/1 NO3). This was followed by some indication of a drop in MetHb levels despite the continued exposure and finally a return to normal levels when the exposure to nitrates stopped. No clinical signs of methemoglobinemia developed. The possible existence of an adaption mechanism is suggested but requires further elucidation

Animal science · Biology · Dietary Nitrate · Hemoglobin · Methemoglobin · Methemoglobinemia · Nitrate · Nitrite · Tap water · Biochemistry · Chemistry · Environmental Chemistry · Environmental Engineering · Environmental Science · Heme Oxygenase-1 and Carbon Monoxide · Methemoglobinemia and Tumor Lysis Syndrome · Neonatal Health and Biochemistry · Toxicology

  • Epidemiological and toxicological aspects of nitrates and nitrites in the environment

    Hillel I Shuval, Nachman Gruener•American Journal of Public Health•1972

  • Methemoglobin levels in infants in an area with high nitrate water supply

    L A Shearer, Linzi Shearer et al.•American Journal of Public Health•1972

Citation velocityhistorical
Highly citedNo

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