Health status and quality of life in comorbid physical multimorbidity and depression among adults aged ⩾50 years from low- and middle-income countries

Bibliographic Data

ID19273451
AuthorsMireia Félez-Nóbrega (0000-0002-3484-4119, Research and Development Unit, Parc Sanitari Sant Joan de Déu, Barcelona, Spain, corresponding author), Ai Koyanagi (0000-0002-9565-5004, Research and Development Unit, Parc Sanitari Sant Joan de Déu, Barcelona, Spain)
Year2023
Volume69
Issue5
Pages1250-1259
Publication date2023-08-01
Open AccessYes
TypeARTICLE
VenueInternational Journal of Social Psychiatry (JOURNAL)
Journal identifiersISSN: 0020-7640 • E-ISSN: 1741-2854
PublisherSAGE Publications (PUBLISHER • US)
DOI10.1177/00207640231157253
PMID36825661
OpenAlexW4321748445
LanguageEN
Citations received2
References cited48

BACKGROUND: Data on the clinical and functional significance of comorbid depression in physical multimorbidity in middle-aged and older adults and from low- and middle-income countries (LMICs) are lacking. AIMS: This study aims to determine the association of comorbid depression in physical multimorbidity with health outcomes and quality of life among adults aged ⩾50 years from six LMICs. METHODS: Cross-sectional, nationally representative data from the Study on Global Ageing and Adult Health were analyzed. DSM-IV Depression was based on past 12-month symptoms. Eleven chronic physical conditions were assessed. Health status was based on scales ranging from 0 (best) to 100 (worse). The quality of life (8-item WHO Quality of Life) scale ranged from 0 (worse) to 100 (best). Multivariable linear regression analyses were conducted. RESULTS: Data on 34,129 individuals aged ⩾50 years [mean (SD) age 62.4 (16.0) years; 52.1% females] were analyzed. Among people with physical multimorbidity, having comorbid depression was associated with significantly worse health status in terms of sleep/energy (β = 14.71: 95% CI [12.23, 17.20]), self-care (13.23: [8.66, 17.82]), pain/discomfort (13.03: [9.59, 16.47]), mobility (11.06: [6.91, 15.21]), cognition (10.41: [7.31, 13.50]), perceived stress (8.35: [4.71, 11.99]), interpersonal activities (7.81: [3.71, 11.91]), and lower quality of life (-8.81: [-10.74, -6.88]). CONCLUSIONS: Comorbid depression in physical multimorbidity was associated with lower quality of life and poorer scores in multiple domains of health status. Treatment of depression in people with physical multimorbidity may potentially lead to better clinical outcomes, but future studies are needed to determine the most effective intervention to address this comorbidity in LMICs

Comorbidity · Cross-sectional study · Depression (economics) · Mental health · Multimorbidity · Psychiatry · Quality of life (healthcare) · Chronic Disease Management Strategies · Demography · Diabetes Management and Education · Interprofessional Education and Collaboration · Medicine · Gerontology

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