Social Stress Influences Tumor Growth
Bibliographic Data
| ID | 19301230 |
|---|---|
| Authors | Lawrence S Sklar (Concordia University, corresponding author), Hymie Anisman (Carleton University) |
| Year | 1980 |
| Volume | 42 |
| Issue | 3 |
| Pages | 347-365 |
| Publication date | 1980-05-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Psychosomatic Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0033-3174 • E-ISSN: 1534-7796 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) (PUBLISHER) |
| DOI | 10.1097/00006842-198005000-00005 |
| PMID | 7192420 |
| OpenAlex | W2333940864 |
| Language | EN |
| Citations received | 4 |
Growth of syngeneic P815 mastocytoma in DBA/2J male mice was evaluated following social and physical stress exposure. Although social isolation following tumor cell transplantation enhanced tumor growth, it appeared that it was the abrupt change in social conditions, rather than the isolation per se which was responsible for the exacerbation of tumorigenicity. Moreover, it was found that the animals' behavior after social change could modify this effect. If mice engaged in persistent fighting, the tumorigenic consequences of social change were not apparent. In addition, it was observed that social conditions interacted with physical stress. Footshock enhanced tumor growth among group housed mice, but retarded tumor development among socially isolated mice
Biology · Developmental psychology · Exacerbation · Psychiatry · Social isolation · Social stress · Immunology · Neurobiology and Insect Physiology Research · Neuroendocrine regulation and behavior · Olfactory and Sensory Function Studies · Psychology
| Citations per year | 0.09 |
|---|---|
| Citation span | 1982 - 2001 (20) |
| Highly cited | No |