Shared neuroendocrine patterns of post-traumatic stress disorder and alexithymia
Bibliographic Data
| ID | 19301669 |
|---|---|
| Authors | James P Henry (0000-0003-1942-1369, Loma Linda University), Mark G Haviland (0009-0002-2642-1586, Loma Linda University), Michael A Cummings (0000-0001-7357-4097, Loma Linda University), D L Anderson, Don Anderson (Loma Linda University), J Craig Nelson (Loma Linda University), James P Macmurray (Loma Linda University), William H McGhee (Loma Linda University), R W Hubbard (Loma Linda University) |
| Year | 1992 |
| Volume | 54 |
| Issue | 4 |
| Pages | 407-415 |
| Publication date | 1992-07-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Psychosomatic Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0033-3174 • E-ISSN: 1534-7796 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) (PUBLISHER) |
| DOI | 10.1097/00006842-199207000-00003 |
| PMID | 1323858 |
| OpenAlex | W2321632832 |
| Language | EN |
| Citations received | 9 |
High norepinephrine/cortisol ratios have been shown to be useful indicators of post-traumatic stress disorder (PTSD). Alexithymia can result from overwhelming stress; thus, we hypothesized that sympathetic-adrenal medullary/hypothalamic-pituitary adrenal ratios would be positively associated with alexithymia severity. In the present study, we correlated 3-methoxy-4-hydroxyphenylethylene glycol (MHPG)/adrenocorticotropic hormone (ACTH) and MHPG/cortisol ratios with self-report Toronto Alexithymia Scale (TAS) scores in a group (n = 17) of nondepressed, formerly alcohol-dependent men. The correlations between the respective ratios and TAS scores were 0.515 (p = 0.034) and 0.561 (p = 0.019). We suggest that increasing degrees of alexithymia are accompanied by an increasing separation of these two endocrine systems and then speculate that this dissociation has an anatomical basis in the lateralization of emotions
Adrenocorticotropic hormone · Alexithymia · Dopamine · Hormone · Norepinephrine · Toronto Alexithymia Scale · Clinical Psychology · Endocrinology · Fibromyalgia and Chronic Fatigue Syndrome Research · Internal Medicine · Medicine · Psychology · Psychosomatic Disorders and Their Treatments · Traumatic Brain Injury Research
The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders
Hormonal abnormalities in alexithymia
Abuse-Related Posttraumatic Stress Disorder and Alterations of the Hypothalamic-Pituitary-Adrenal Axis in Women With Chronic Pelvic Pain
Treatment of Posttraumatic Stress Disorder
Posttraumatic Stress Disorder Revisited
Urinary Catecholamines and Cortisol in Recent-Onset Posttraumatic Stress Disorder After Motor Vehicle Accidents
The effects of early relational trauma on right brain development, affect regulation, and infant mental health
Psychological and physiological responses to stress
The role of blood pressure, cortisol, and prolactine among soldiers injured in the 1991–1993 war in Croatia
| Citations per year | 0.27 |
|---|---|
| Citation span | 1993 - 2023 (31) |
| Highly cited | No |