Patterns of adrenergic receptors and adrenergic agonists underlying cardiovascular responses to a psychological challenge
Bibliographic Data
| ID | 19302979 |
|---|---|
| Authors | Paul J Mills (0000-0003-4263-7686, University of San Diego), J E Dimsdale (University of San Diego), Richard A Nelesen (University of San Diego), J Jasiewicz (University of San Diego), Michael G Ziegler (0000-0002-0841-350X, University of San Diego), Barbara L Kennedy (University of San Diego), B Kennedy |
| Year | 1994 |
| Volume | 56 |
| Issue | 1 |
| Pages | 70-76 |
| Publication date | 1994-01-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Psychosomatic Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0033-3174 • E-ISSN: 1534-7796 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) (PUBLISHER) |
| DOI | 10.1097/00006842-199401000-00009 |
| PMID | 8197317 |
| OpenAlex | W2322309082 |
| Language | EN |
| Citations received | 6 |
Numerous physiological and biochemical factors contribute to the dynamic regulation of the cardiovascular system. This study used a cluster analytic statistical technique to discern patterns of adrenergic receptors and adrenergic agonists underlying cardiovascular responses to a laboratory challenge. Fifty hypertensive and normotensive black and white individuals had their beta- and alpha-adrenergic receptor sensitivity determined through agonist infusions. Norepinephrine, epinephrine, blood pressure, and heart rate responses to a standardized mental arithmetic task were also obtained. The cluster analysis identified four subgroups of individuals having distinct patterns of receptor and neurohormonal regulation of end-organ responses. In general, the data indicated that end-organ cardiovascular responses are, in part determined by the sensitivity of adrenergic receptors and the accompanying catecholamine responses. The findings also suggest that for some individuals nonadrenergic factors play a more dominant role than adrenergic mechanisms in determining cardiovascular pressor responses
Adrenergic · Adrenergic agonist · Adrenergic receptor · Agonist · Alpha-1B adrenergic receptor · Alpha-2 adrenergic receptor · Beta-3 adrenergic receptor · Blood pressure · Catecholamine · Dopamine · Epinephrine · Heart rate · Norepinephrine · Receptor · Sympathetic nervous system · Endocrinology · Heart Rate Variability and Autonomic Control · Internal Medicine · Medicine · Stress Responses and Cortisol
Consultation-Liaison Psychiatry and Psychosomatic Medicine
The use and reporting of cluster analysis in health psychology
Cardiovascular and plasma catecholamine response to static exercise in normotensive blacks and whites
The Relationship Between Hostility and beta-Adrenergic Receptor Physiology in Healthy Young Males
An Historical and Critical Review of the Articles on Blood Pressure Published in Psychosomatic Medicine Between 1939 and 1997
Psychophysiological Reactivity
| Unique citing works | 6 |
|---|---|
| Citations per year | 0.21 |
| Citation span | 1997 - 2005 (9) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 5 |