Changes in Emotional Vitality as a Predictor of Levels and Change in Allostatic Load

Longitudinal Results From the Whitehall II Cohort Study

Bibliographic Data

ID19303170
AuthorsLaura Deen (0000-0003-4443-7098, Frederiksberg Hospital, corresponding author), Nadya Dich (0000-0002-3631-0161), Josephine Head (0000-0002-6054-0872), Jenny Head, A J Clark (0000-0002-9305-4504)
Year2020
Volume82
Issue4
Pages432-439
Publication date2020-05-01
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/psy.0000000000000791
PMID32108741
OpenAlexW3007525269
LanguageEN
Citations received2
References cited41

OBJECTIVE: Increasing evidence has shown an association between reduced psychological well-being and long-term morbidity. However, longitudinal studies addressing potential biobehavioral mechanisms, such as physiological function, are lacking. The aim of this study is to examine the association between changes in emotional vitality on levels and changes in allostatic load (AL), a measure of multisystem physiological dysregulation, as well as its composite risk markers. METHODS: Participants comprised 5919 British civil servants from phases 3, 5, and 7 of the Whitehall II study. Psychological well-being was operationalized as emotional vitality. AL was measured using nine biomarkers of the cardiovascular, metabolic, and immune system. Linear mixed-effect models were used to determine the association between changes in emotional vitality between phases 3 and 5 and subsequent levels and change in AL from phases 5 to 7. Generalized linear models were used to address the association between changes in emotional vitality and individual risk markers. RESULTS: Increase in emotional vitality was associated with a lower mean level of AL, whereas the AL slope was not markedly affected. Among the included risk markers, only interleukin-6 was weakly associated with changes in emotional vitality, with a 7% reduced risk of high levels of interleukin-6 per one-unit increase in emotional vitality. CONCLUSION: This study found that an increase in emotional vitality was associated with subsequent lower levels, but not rate of change, of AL over time. Further research is needed to address the relationship between trajectories of psychological well-being and physiological dysregulation

Allostatic load · Association (psychology) · Cohort · Longitudinal study · Vitality · Cardiac Health and Mental Health · Clinical Psychology · Demography · Internal Medicine · Medicine · Psychological Well-being and Life Satisfaction · Psychology · Stress Responses and Cortisol · Gerontology

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