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Erectile Dysfunction

Evaluation and New Treatment Options

Bibliographic Data

ID19305693
AuthorsCulley C Carson (University of North Carolina at Chapel Hill, corresponding author)
Year2004
Volume66
Issue5
Pages664-671
Publication date2004-09-01
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/01.psy.0000133969.80612.71
PMID15385689
OpenAlexW2027581431
LanguageEN
Citations received2
References cited43

OBJECTIVE: Erectile dysfunction (ED) is a common condition of aging men. Indeed as many as 50% of men over age 40 will suffer some degree of ED. This erectile dysfunction has substantial impact on interaction with their partners, families, and employment. ED may be a harbinger of more serious vascular events and is commonly associated with depression. METHODS: Evaluation of ED begins with a careful history, asking the patient about his sexual function during clinical visits. Once identified, ED must be carefully considered with full history, careful physical examination, and laboratory studies to include markers of vascular risk factors, diabetes, and hypogonadism. RESULTS: The treatment of ED was revolutionized by the introduction of phosphodiesterase type 5 (PDE5) inhibitors in 1998. Currently, 3 PDE5 inhibitors are available internationally with excellent expected results and somewhat unique profiles. Although these agents are safe in all patients who do not have severe cardiac disease or who are taking nitrate medications, they require some patient instruction and counseling to optimize results. In that small group of patients who do not respond to these oral medications, additional alternatives are available for patients motivated to pursue treatment of their ED. CONCLUSION: Currently available safe and effective alternatives for the treatment of ED can improve the lives of patients and partners and increase their quality of life

cGMP-specific phosphodiesterase type 5 · Cyclic guanosine monophosphate · Depression (economics) · Disease · Erectile dysfunction · Erectile function · Intensive care medicine · Nitric oxide · Quality of life (healthcare) · Hormonal and reproductive studies · Internal Medicine · Medicine · Phosphodiesterase function and regulation · Sexual function and dysfunction studies

  • A Multicenter, Randomized, Open-Labeled, Parallel Group Trial of Sildenafil in Alcohol-Associated Erectile Dysfunction

    Open Access•Alexander M Ponizovsky, Lev Averbuch et al.•International Journal of…•2009

  • Screening for Rho-kinase 2 inhibitory potential of Indian medicinal plants used in management of erectile dysfunction

    Open Access•Sumanta Kumar Goswami, Sumanta Goswami et al.•Journal of Ethnopharmacology•2012

  • Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (Iief-5) as a diagnostic tool for erectile dysfunction

    Open Access•RC Rosen, JC Cappelleri et al.•International Journal of…•1999

  • Impotence and Its Medical and Psychosocial Correlates

    Open Access•Henry A Feldman, Irwin Goldstein et al.•The Journal of Urology•1994

  • Sexual Dysfunction in the United States

    Edward O Laumann, A Paik et al.•JAMA•1999

Citations per year0.12
Citation span2009 - 2012 (4)
Highly citedNo

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