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Psychoendocrine Aspects of Cancer of the Breast

Bibliographic Data

ID19306149
AuthorsJack L Katz (Montefiore Hospital), Phyllis Ackman (Montefiore Hospital), YONA ROTHWAX (Montefiore Hospital), EDWARD J SACHAR (Montefiore Hospital), Herbert Weiner (Montefiore Hospital), Leon Hellman (Montefiore Hospital), T F Gallagher (0000-0001-6381-6902, Montefiore Hospital)
Year1970
Volume32
Issue1
Pages1-18
Publication date1970-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/00006842-197001000-00001
PMID5418290
OpenAlexW2322778954
LanguageEN
Citations received3
References cited4

Thirty women in the hospital awaiting biopsy of a breast tumor were interviewed in order to assess the adequacy of their ego defenses in this presumably threatening situation. The criteria for this psychological evaluation were the patient's affective state, functional disruption, and defensive reserve impairment. Concurrent with these assessments, daily production rates of hydrocortisone and urinary excretion levels of the principal hydrocortisone and androgen metabolites were measured. A rank order correlation significant at the .02 level was found between rating scores for extent of defensive failing and hydrocortisone production rates, and at the .05 level between this psychological variable and the principal hydrocortisone metabolites; however, no correlation existed with the androgen metabolites. Since other studies have indicated a correlation between prognosis in breast cancer and a numerical ratio calculated on the basis of the patient's endogenous corticoid to androgenic steroids, this study raises questions about the determination and nature of such a ratio and about the possible role of psychological phenomena in the course of this neoplasm

Androgen · Breast cancer · Cancer · Correlation · Hormone · Hydrocortisone · Endocrinology · Estrogen and related hormone effects · Hormonal Regulation and Hypertension · Internal Medicine · Medicine · Physiology · Psychology · Stress Responses and Cortisol

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    Open Access•Steven Greer, Tina Morris et al.•Social Science & Medicine Medical…•1978

  • Epistemological perspectives of physical disease from the psychodynamic point of view

    CLAUS BAHNE BAHNSON•American Journal of Public Health•1974

  • A Review of Psychoendocrine Research on the Pituitary-Adrenal Cortical System

    John Mason, John W Mason•Psychosomatic Medicine•1968

  • Preoperative Psychological State and Corticosteroid Levels of Surgical Patients

    Ben Bursten, Jonathan Jay Russ•Psychosomatic Medicine•1965

  • Influence of the Hypnotic Trance on Plasma 17-Hydroxycorticosteroid Concentration

    EDWARD J SACHAR, Jacob R Fishman et al.•Psychosomatic Medicine•1965

  • Psychoendocrine Aspects of Acute Schizophrenic Reactions

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Unique citing works3
Citations per year0,06
Citation span1974 - 1991 (18)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 3

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