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Association Between Low Plasma Levels of Cholesterol and Relapse in Cocaine Addicts

Bibliographic Data

ID19306938
AuthorsLaure Buydens-Branchey, Laure Buydens‐Branchey (State University of New York), Marc Branchey (VA NY Harbor Healthcare System)
Year2003
Volume65
Issue1
Pages86-91
Publication date2003-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/01.psy.0000039754.23250.ee
PMID12554819
OpenAlexW2009764852
LanguageEN
Citations received2
References cited45

OBJECTIVE: In light of recent studies suggesting the existence of associations between low concentrations of cholesterol and various psychiatric disorders, we decided to explore relationships between cholesterol levels and relapse rates in a group of cocaine addicts who had undergone inpatient detoxification. METHODS: The total cholesterol levels of 38 non-opiate-dependent and non-alcohol-dependent cocaine addicts were determined while they were hospitalized. Drug use was subsequently assessed 3, 6, and 12 months after patients were discharged from the hospital. RESULTS: Comparisons of the cholesterol levels (obtained during hospitalization) of relapsers and nonrelapsers by analyses of covariance with age and weight as covariates revealed significantly lower cholesterol values in patients who relapsed at 3 months (p =.046), 6 months (p =.030), and 12 months (p =.019) after discharge. CONCLUSIONS: This study showed an association between a low total cholesterol level and relapse rates in detoxified cocaine addicts. Reasons for the predictive value of low cholesterol levels for relapse for up to 1 year after cholesterol measurements were made are unclear. These data are preliminary and in need of replication

Addiction · Cholesterol · Detoxification (alternative medicine) · Hypocholesterolemia · Opiate · Psychiatry · Alcohol Consumption and Health Effects · Forensic Toxicology and Drug Analysis · Internal Medicine · Medicine · Substance Abuse Treatment and Outcomes

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Unique citing works2
Citations per year0.5
Citation span2022 - 2023 (2)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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