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Diagnostic Procedures, Revascularization, and Inpatient Mortality After Acute Myocardial Infarction in Patients With Schizophrenia and Bipolar Disorder

Bibliographic Data

ID19306992
AuthorsShu‐I Wu (0000-0002-8461-5613, King's College London), Shu-I Wu, Su-Chiu Chen, Su‐Chiu Chen, Jimmy J M Juang, Chun‐Kai Fang (0000-0002-5071-3151), Chun-Kai Fang, Shen-Ing Liu, Shen‐Ing Liu, Fang‐Ju Sun, Fang-Ju Sun, Kai‐Liang Kao (corresponding author), Kai-Liang Kao, Michael Dewey (0000-0002-7522-3677), Martin J Prince (0000-0003-2888-2394), Martin Prince (0000-0003-1379-7146), Robert Stewart (0000-0002-6326-915X)
Year2013
Volume75
Issue1
Pages52-59
Publication date2013-01-01
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/psy.0b013e31827612a6
PMID23213265
OpenAlexW2062787728
LanguageEN
Citations received2
References cited36

OBJECTIVE: To investigate inpatient mortality and the use of invasive diagnostic and revascularization procedures after acute myocardial infarction (AMI) in people with schizophrenia and bipolar disorder. METHODS: A case-control study was nested within the first AMI episodes between 1996 and 2007 using nationwide data. Participants with schizophrenia or bipolar disorder were compared with a random sample of all other adults without severe mental illness. Inpatient mortality and receipt of cardiac catheterization, coronary arteriography, percutaneous transluminal coronary angioplasty, and coronary artery bypass graft were compared in logistic regression models after adjusting for demographic and health status, hospital type, and AMI complications. RESULTS: A total of 3361 adult patients who had incident AMI between 1996 and 2007 were identified. Patients with schizophrenia and bipolar disorder (n = 834; 24.8%) had a significantly decreased likelihood of catheterization (12.2% and 14.0%, respectively) and revascularization (9.0% and 12.8%, respectively) during the index AMI episode compared with controls (27.9% of whom received catheterization and 23.9% of whom received revascularizations). Inpatient mortality remained 2.68 times the rate in patients with schizophrenia (95% confidence interval = 1.73-4.15; p < .001) compared with controls after adjusting for intervention receipt among other covariates, but mortality was not significantly raised in patients with bipolar disorder. CONCLUSIONS: In a large national sample and in the context of a comprehensive free health service, patients with schizophrenia and bipolar disorder were substantially disadvantaged, being half as likely to receive catheterization or revascularization procedures after AMI. Further research is required to clarify the reasons for this

Bipolar disorder · Cardiology · Myocardial infarction · Psychiatry · Revascularization · Schizophrenia (object-oriented programming) · Cardiac electrophysiology and arrhythmias · Cardiac Health and Mental Health · Emergency Medicine · Internal Medicine · Medicine · Schizophrenia research and treatment

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Citations per year0.2
Citation span2016 - 2020 (5)
Highly citedNo

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