Serum Gastrin and the Family Environment in Duodenal Ulcer Disease

Bibliographic Data

ID19307405
AuthorsDeane L Wolcott (Neurobehavioral Systems), David K Wellisch (Neurobehavioral Systems), Charlotte Robertson (0000-0002-5956-5191, Neurobehavioral Systems), Charlotte R Robertson, Ransom J Arthur (Neurobehavioral Systems)
Year1981
Volume43
Issue6
Pages501-507
Publication date1981-12-01
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/00006842-198112000-00006
PMID6976585
OpenAlexW2318001979
LanguageEN
Citations received1
References cited3

The study investigated the relationships between specific demographic, psychosocial, and physiological variables and the severity of duodenal ulcer disease in a population of patients with proved duodenal ulcer. Intercorrelations between psychosocial and physiological variables were also studied. The study design was cross sectional and retrospectively assessed life change units and DUD severity during the previous 6 months in 39 male ulcer clinic outpatients. Anxiety, depression, life change units, the family environment, ABO blood type, secretor status, serum pepsinogen, and serum fasting gastrin were evaluated. A DUD severity score was calculated from self-reported ulcer pain symptoms and ulcer complications. Gastrin levels correlated significantly with three Family Environment Scale (FES) subscales, including: (a) independence, (b) achievement orientation, and (c) expressiveness. Duodenal ulcer disease severity scores correlated with Zung SDS scores, but not with state or trait anxiety, life change units, or the FES

ABO blood group system · Anxiety · Disease · Duodenal ulcer · Gastrin · Population · Psychiatry · Psychosocial · Eosinophilic Esophagitis · Gastroenterology · Gastrointestinal motility and disorders · Helicobacter pylori-related gastroenterology studies · Internal Medicine · Medicine

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