End-of-Life Care Among Patients With Bipolar Disorder and Cancer
A Nationwide Cohort Study
Bibliographic Data
| ID | 19307673 |
|---|---|
| Authors | Guillaume Fond (0000-0003-3249-2030, Fondation FondaMental, corresponding author), Karine Baumstarck (0000-0003-3602-6766), Pascal Auquier (0000-0003-3496-1996), Vanessa Pauly (0000-0003-1346-1781), Cécile Bernard (0000-0003-3590-0060), Veronica Orléans, Pierre-Michel Llorca, Pierre‐Michel Llorca (0000-0001-7438-8990), Christophe Lançon (0000-0002-0661-5781), Sébastien Salas (0000-0001-6222-5027), Laurent Boyer (0000-0002-1375-1706) |
| Year | 2020 |
| Volume | 82 |
| Issue | 7 |
| Pages | 722-732 |
| Publication date | 2020-09-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Psychosomatic Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0033-3174 • E-ISSN: 1534-7796 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) (PUBLISHER) |
| DOI | 10.1097/psy.0000000000000839 |
| PMID | 32665480 |
| OpenAlex | W3043420026 |
| Language | EN |
| References cited | 35 |
OBJECTIVE: This study aimed to describe end-of-life (EOL) care in individuals with bipolar disorder (BD) who died of cancer compared with mentally healthy individuals. METHODS: This was a nationwide cohort study of all adult individuals who died of cancer in hospitals in France between 2013 and 2016. Outcomes were compared between individuals with BD and mentally healthy individuals in the last month of life including palliative care and high-intensity EOL care (chemotherapy, artificial nutrition, and other interventions). A subanalysis explored differences between patients with BD and patients with schizophrenia. RESULTS: The study included 2015 individuals with BD and 222,477 mentally healthy controls. Compared with the controls, individuals with BD died 5 years earlier, more often had comorbidities and thoracic cancer, and had fewer metastases, but did not have shorter delays from cancer diagnosis to death. After matching and adjustment for covariates, individuals with BD more often received palliative care in the last 3 days of life (25% versus 13%, p < .001) and less high-intensity care (e.g., chemotherapy 12% versus 15%, p = .004), but more artificial nutrition (6% versus 4.6%, p = .003). Compared with the schizophrenia comparison group, chemotherapy was received more by individuals with BD in the last 14 days of life (12.5% for BD versus 9.4%, p < .001). CONCLUSIONS: Individuals with BD were more likely to receive palliative care and less likely to receive high-intensity EOL care, except for artificial nutrition. These results may not be specific to BD, as no difference was found between patients with BD and schizophrenia except for chemotherapy
Bipolar disorder · Cancer · Chemotherapy · Cohort · Cohort study · End-of-life care · Palliative care · Psychiatry · Psychological intervention · Schizophrenia (object-oriented programming) · Bipolar Disorder and Treatment · Internal Medicine · Medicine · Palliative Care and End-of-Life Issues · Schizophrenia research and treatment
Associations Between End-of-Life Discussions, Patient Mental Health, Medical Care Near Death, and Caregiver Bereavement Adjustment
Mortality in Mental Disorders and Global Disease Burden Implications
Ecological association between a deprivation index and mortality in France over the period 1997 – 2001
Coding Algorithms for Defining Comorbidities in ICD-9-CM and ICD-10 Administrative Data
| Citation velocity | historical |
|---|---|
| Highly cited | No |