Overview of HIV
Bibliographic Data
| ID | 19308024 |
|---|---|
| Authors | Nancy Klimas, Nancy G Klimas (0000-0003-1459-3268, University of Miami, corresponding author), Anne O’Brien Koneru, Mary Ann Fletcher |
| Year | 2008 |
| Volume | 70 |
| Issue | 5 |
| Pages | 523-530 |
| Publication date | 2008-06-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Psychosomatic Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0033-3174 • E-ISSN: 1534-7796 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) (PUBLISHER) |
| DOI | 10.1097/psy.0b013e31817ae69f |
| PMID | 18541903 |
| OpenAlex | W2060044770 |
| Language | EN |
| Citations received | 3 |
| References cited | 38 |
This article provides an overview and reviews the HIV pandemic, the basic biology and immunology of the virus (e.g., genetic diversity of HIV and the viral life cycle), the phases of disease progression, modes of HIV transmission, HIV testing, immune response to the infection, and current therapeutic strategies. HIV is occurring in epidemic proportions, especially in Sub-Saharan Africa. In the US, men who have sex with men account for over half of AIDS diagnoses; racial and ethnic minorities are disproportionally affected. Factors influencing the progression and severity of HIV infection include type of immune response, coinfection (e.g., another sexually transmitted infection, including hepatitis B or C), age and behavioral and psychosocial factors. Antiretroviral therapies can achieve reduction in blood levels of the HIV virus below the limits of detection by current technology. However, effective treatment requires adherence to therapy. Patient failure to adhere to treatment regimens results in detectible circulating virus and in HIV disease progression, and is the primary cause of drug resistance. In addition to research on the immunology and virology of the disease, other studies focus on behavioral and psychosocial factors that may affect medication adherence and risk behaviors
Coinfection · Disease · Hepatitis C virus · Immune system · Pneumonia · Psychiatry · Psychosocial · Viral load · Virus · HIV Research and Treatment · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Immunology · Internal Medicine · Medicine
Epidemiology of health and vulnerability among children orphaned and made vulnerable by HIV/Aids in sub-Saharan Africa
Co-occurrence of Treatment Nonadherence and Continued HIV Transmission Risk Behaviors
Do Positive Psychosocial Factors Predict Disease Progression in HIV-1? A Review of the Evidence
Role of Depression, Stress, and Trauma in HIV Disease Progression
Coping as a Multisystem Construct Associated With Pathways Mediating HIV-Relevant Immune Function and Disease Progression
HIV Prevention for Injecting Drug Users
Modelling the evolution of drug resistance in the presence of antiviral drugs
HIV seropositivity of needles from shooting galleries in south Florida
| Unique citing works | 3 |
|---|---|
| Citations per year | 0,17 |
| Citation span | 2008 - 2023 (16) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 2 |