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The Electroencephalogram and Psychopathological Manifestations in Schizophrenia as Influenced by Drugs1

Bibliographic Data

ID19308124
AuthorsMorton A Rubin (Worcester Memorial Hospital), William Malamud (Worcester Memorial Hospital), JUSTIN M HOPE (Worcester Memorial Hospital)
Year1942
Volume4
Issue4
Pages355-361
Publication date1942-10-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/00006842-194210000-00002
OpenAlexW2327475162
LanguageEN
Citations received3

Mescaline, cocaine, sodium amytal and benzedrine were given to 14 schizophrenic patients, and their influence upon personality functions and the electroencephalogram (EEG) was observed. Changes in the EEG were found only when definite psychological changes took place. The effects of the drugs could be classified into two types: 1) Those specific for a given drug. Psychologically these were manifested in changes in attitude, anxiety, mood, etc. Correlated with the most extreme states of anxiety produced by mescaline was a 25 to 30 per cent increase in frequency of the 10-per-second (alpha) rhythm. With sodium amytal the decreased tension was accompanied by the appearance of a 15 to 20-persecond (beta) rhythm. 2) Those characteristic of a given patient. Psychologically these took the form of elaborations within the content of the psychosis and the patient's reaction to the setting, regardless of which drug was used. Similarly, a change in per cent time alpha of the EEG was consistent in a given patient either in the direction of increase or decrease

Alpha (finance) · Alpha rhythm · Anxiety · Audiology · Electroencephalography · Hallucinogen · Mescaline · Mood · Personality · Psychiatry · Psychoanalysis · Psychometrics · Psychopathology · Schizophrenia (object-oriented programming) · Clinical Psychology · Medicine · Neurotransmitter Receptor Influence on Behavior · Psychology · Schizophrenia research and treatment

  • Electroencephalography

    R Gilman, Robert Tucker Gilman•Psychological Bulletin•1944

  • Drugs

    Open Access•Bernard S Aaronson•Psychological Reports•1970

  • Shifts Along the Alert-Repose Continuum During Remission of Catatonic "Stupor" with Amobarbital

    John M Stevens, John Stevens et al.•Psychosomatic Medicine•1958

Unique citing works3
Citations per year0.04
Citation span1944 - 1970 (27)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 2

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