Female Gender Is Associated With Impaired Quality of Life 1 Year After Coronary Artery Bypass Surgery

Bibliographic Data

ID19308299
AuthorsBarbara Phillips Bute (Duke University, corresponding author), Joseph P Mathew (0000-0002-3815-4131), Joseph Mathew, James A Blumenthal (0000-0003-3789-0935), Kathleen A Welsh‐Bohmer (0000-0003-1824-0179), Kathleen Welsh-Bohmer, William D White (0000-0002-2969-2798), Daniel B Mark (0000-0001-6340-8087), Daniel Mark, Kevin Landolfo (0000-0003-4256-6881), Mark F Newman (0000-0003-4851-015X)
Year2003
Volume65
Issue6
Pages944-951
Publication date2003-11-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/01.psy.0000097342.24933.a2
PMID14645771
OpenAlexW1481669777
LanguageEN
Citations received7
References cited31

OBJECTIVE: To evaluate gender-related differences in quality of life (QOL) and cognitive function 1 year after coronary artery bypass surgery (CABG) after adjusting for known baseline differences. MATERIALS AND METHODS: Two hundred eighty patients (96 women and 184 men) underwent neurocognitive and QOL evaluation at baseline (preoperatively) and at 1 year after CABG. Multivariable linear regression was used to assess the relationship of gender to follow-up QOL and cognitive function. Measures used to evaluate QOL were IADL, DASI, work activities (SF-36), social activities, social support, general health perception (SF-36), CESD, STAI, and symptom limitations. Cognitive function was measured with a battery of performance-based neuropsychological tests, reduced to a four-cognitive domain scores with factor analysis, and a self-report measure of cognitive difficulties. Covariates in multiple regression models included age, years of education, marital status, Charlson Comorbidity Index, hypertension, diabetes, race, and baseline QOL/cognitive status. RESULTS: Female patients showed significantly worse outcome than male patients at 1 year follow-up in several key areas of QOL. After adjusting for baseline differences, women are at greater risk for increased cognitive difficulties (p= 0.04) and anxiety (p= 0.03), as well as impaired DASI (p= 0.02), IADL (p= 0.03), and work activities (p= 0.02). Cognitive sequelae attributable to bypass surgery were similar between men and women. CONCLUSIONS: Even after adjusting for known risk factors for compromised QOL and cognitive functioning, women do not show the same long-term quality benefits of CABG surgery that men do

Artery · Cardiology · Coronary artery bypass surgery · Quality of life (healthcare) · Aortic Disease and Treatment Approaches · Cardiac and Coronary Surgery Techniques · Cardiac Health and Mental Health · Internal Medicine · Medicine · Nursing · Surgery

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