Learned Symptom-Specific Fear Toward a Visceral Sensation and Its Impact on Perceptual Habituation
Bibliographic Data
| ID | 19308345 |
|---|---|
| Authors | Lauren Pattyn (0000-0002-1188-1929, KU Leuven, corresponding author), Jonas Zaman (0000-0002-2218-3018, Allen Institute for Brain Science), Iris van de Pavert (0000-0002-3973-2220, Allen Institute for Brain Science), Valentina Jelinčić (0000-0002-7588-3720, Allen Institute for Brain Science), Andreas von Leupoldt (0000-0001-8539-8131, Allen Institute for Brain Science), Lukas Van Oudenhove (0000-0002-6540-3113, Allen Institute for Brain Science), Ilse Van Diest (0000-0002-0048-774X, Allen Institute for Brain Science) |
| Year | 2024 |
| Volume | 86 |
| Issue | 9 |
| Pages | 790-799 |
| Publication date | 2024-11-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Psychosomatic Medicine (JOURNAL) |
| Journal identifiers | ISSN: 0033-3174 • E-ISSN: 1534-7796 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) (PUBLISHER) |
| DOI | 10.1097/psy.0000000000001345 |
| PMID | 39317166 |
| OpenAlex | W4402789249 |
| Language | EN |
| References cited | 66 |
OBJECTIVE: Impaired habituation of bodily sensations has been suggested as a contributing factor to chronic pain. We examined in healthy volunteers the influence of fear learning toward a nonpainful sensation in the esophagus on the perceptual habituation of this sensation. METHODS: In a homoreflexive fear learning paradigm, nonpainful electrical sensations in the esophagus were used as a conditioned stimulus (CS). This sensation was presented 42 times before, during, and after fear learning. In the fear learning group ( n = 41), the CS was paired with a painful electrical sensation in the esophagus (unconditioned stimulus [US]). In the control group ( n = 41), the CS was not paired with the US. Ratings for CS intensity, US expectancy, startle electromyogram (EMG), skin conductance responses (SCR), and event-related potentials (ERPs) to the CS were assessed. RESULTS: Compared to the control group, fear learning was observed in the fear learning group as evidenced by potentiated startle responses after the CS relative to ITI ( t (1327) = 3.231, p = .001) and higher US expectancy ratings ( t (196) = 3.17, p = .002). SCRs did not differ between groups ( F1,817 = 1.241, p = .33). Despite successful fear learning, the fear learning group did not show a distinct pattern of habituation to the visceral CS relative to the control group (intensity ratings: F1,77.731 = 0.532, p = .47; ERPs: F1,520.78 = 0.059, p = .94). CONCLUSION: Acquired fear to nonpainful esophageal sensations does not affect their perceptual habituation patterns
Audiology · Cognitive psychology · Developmental psychology · Expectancy theory · Habituation · Perception · Reflex · Sensation · Startle reaction · Stimulus (psychology) · Heart Rate Variability and Autonomic Control · Medicine · Neuroscience · Pain Management and Treatment · Pain Mechanisms and Treatments · Psychology · Social Psychology
| Citation velocity | historical |
|---|---|
| Highly cited | No |