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Well-Being Therapy and Lifestyle Intervention in Type 2 Diabetes

A Pilot Randomized Controlled Trial

Bibliographic Data

ID19309299
AuthorsGiada Benasi (0000-0002-1537-6655, Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author), Sara Gostoli (0000-0002-5828-4654), Boheng Zhu (0000-0001-8506-1977), Emanuela Offidani (0000-0003-3348-3494), Michael G Artin (0000-0002-9872-305X), L Gagliardi (0000-0002-7398-7219), Giovanni Rignanese, Graziella Sassi, Giovanni A Fava (0000-0002-1690-5344), Chiara Rafanelli (0000-0003-3025-7918)
Year2022
Volume84
Issue9
Pages1041-1049
Publication date2022-11-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenuePsychosomatic Medicine (JOURNAL)
Journal identifiersISSN: 0033-3174 • E-ISSN: 1534-7796
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/psy.0000000000001115
PMID36346956
OpenAlexW4308687688
LanguageEN
References cited41

OBJECTIVE: This pilot randomized controlled trial evaluates the preliminary efficacy of a 4-month well-being therapy (WBT) and lifestyle intervention among adults with type 2 diabetes and overweight/obesity. METHODS: Fifty-eight patients were recruited from two outpatient clinics and randomized to receive the WBT-lifestyle intervention or the lifestyle intervention alone. Data were collected at baseline (T0), immediate postintervention (T1), 6-month follow-up (T2), and 12-month follow-up (T3). Primary efficacy outcomes included changes in weight, psychological distress, and well-being, whereas secondary efficacy outcomes included changes in lifestyle and physiological parameters. RESULTS: Compared with the lifestyle-alone intervention, the WBT-lifestyle intervention showed greater improvements in depression (p = .009, d = -0.6), hostility (p = .018, d = -0.6), and personal growth (p = .026, d = 0.5) at T1, in self-reported physical activity at T2 (p = .013, d = 0.7) and T3 (p = .040, d = 0.5), and in triglycerides (p = .019, d = -1.12) at T3. There were no differences between treatment groups in weight and other physiological parameters. CONCLUSIONS: These findings suggest that WBT may be a valuable addition to lifestyle interventions for improving short-term psychological outcomes and promoting long-term healthy changes in physical activity, with a potential impact on physiological outcomes.Trial Registration:ClinicalTrials.gov identifier: NCT03609463

Depression (economics) · Diabetes mellitus · Hostility · Obesity · Overweight · Physical therapy · Psychiatry · Psychological intervention · Randomized controlled trial · Type 2 diabetes · Clinical Psychology · Diabetes Management and Education · Internal Medicine · Medicine · Mindfulness and Compassion Interventions · Physical Activity and Health

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