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Alcohol-related intentional nonadherence to antiretroviral therapy among people living with HIV, Cape Town, South Africa

Bibliographic Data

ID19438800
AuthorsSeth Kalichman (University of Connecticut), Seth C Kalichman (0000-0002-0912-5112, University of Connecticut, corresponding author), Catherine Mathews (0000-0001-5368-1127, Health Systems Research Unit, Medical Research Council, Cape Town, South Africa), Ellen Banas (University of Connecticut), Moira O Kalichman (0000-0003-4495-4140, University of Connecticut), Moira Kalichman (University of Connecticut)
Year2019
Volume31
Issue8
Pages951-957
Publication date2019-08-03
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2019.1587357
PMID30884956
OpenAlexW2925122129
LanguageEN
Citations received10
References cited38

Alcohol use may have significant negative impacts on individuals’ ability to remain adherent to antiretroviral therapy (ART), and may also yield other negative psychosocial, health-related, and behavioral outcomes. In addition, false beliefs about the consequences of mixing alcohol with ART use may cause individuals to avoid taking ART when drinking (alcohol-related ART avoidance). Although research conducted in the U.S. and Europe has reported on alcohol-ART avoidance, the current study presents among the first quantitative evidence of alcohol-related intentional ART nonadherence in South Africa. Patients receiving ART from a community clinic in Cape Town (N = 441) completed anonymous surveys of alcohol use, ART adherence, and alcohol-ART avoidance. Results showed that 292 (66%) participants reported current alcohol use; 25% who use alcohol believed that people who drink should stop taking ART when they are drinking and 24% stop their own ART when drinking. Alcohol-ART avoidance mediated the association between alcohol use and ART adherence. Results were robust when controlling for participant age, gender, current care status, and first- versus second-line ART. We found alcohol-ART avoidance may threaten successful ART in South Africa. Corrective messages that take a harm reduction approach to maximize ART adherence when drinking should be implemented in existing clinical services

Alcohol · Antiretroviral therapy · Art Therapy · Family medicine · Harm · Harm reduction · Psychiatry · Psychological intervention · Psychosocial · Viral load · Adolescent Sexual and Reproductive Health · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Psychology · Social Psychology

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Citations per year1.67
Citation span2020 - 2025 (6)
Highly citedNo

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