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Correlates of HIV antiretroviral adherence in persons with serious mental illness

Bibliographic Data

ID19439615
AuthorsGlenn J Wagner (0000-0001-9081-3299, RAND School of Public Policy, corresponding author), David E Kanouse (RAND School of Public Policy), Paul Koegel (RAND School of Public Policy), G Sullivan (a RAND , California , Santa Monica , USA)
Year2004
Volume16
Issue4
Pages501-506
Publication date2004-05-01
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540120410001683420
PMID15203417
OpenAlexW1999555849
LanguageEN
Citations received12
References cited12

Although several studies have examined the relationship between symptoms of depression or psychological distress and medication adherence, this is the first published study of HIV antiretroviral adherence and its correlates among persons diagnosed with serious mental illness. Forty-five of 47 (96%) participants completed a two-week study in which their adherence to antiretroviral medication was measured using electronic monitoring caps. Mean adherence (proportion of prescribed doses taken) was 66% (SD=34). There were several correlates (p<0.05) of adherence among background and medical characteristics, physical symptoms and side effects, cognitive and psychosocial functioning, and treatment-related attitudes and beliefs. However, in a forward stepwise regression, attendance at recent clinical appointments was the sole predictor that entered the model--accounting for 49% of the variance in adherence. Using attendance at recent clinic appointments as the criterion, adherence readiness (90+% adherence to antiretrovirals) was correctly determined for 72% of the sample. Although not sufficient to serve as the basis for treatment decision making, review of appointment-keeping records may provide clinicians with a simple, cost-effective method for predicting adherence to ongoing treatment, as well as for evaluating adherence readiness to inform the decision of whether to prescribe or defer treatment

Attendance · Distress · Medication adherence · Psychiatry · Psychosocial · Stepwise regression · Clinical Psychology · HIV/AIDS Research and Interventions · LGBTQ Health, Identity, and Policy · Medication Adherence and Compliance · Medicine · Internal Medicine

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  • The Treatment Ambassador Program

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Citations per year0.57
Citation span2005 - 2023 (19)
Highly citedNo

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