The risk of HIV and HCV infections among injection drug users in northeast India

Bibliographic Data

ID19439728
AuthorsJagadish Mahanta (a Regional Medical Research Centre, Northeast Region (Indian Council of Medical Research) , P.O. Box-105, Dibrugarh , 786001 , Assam , India, corresponding author), Biswajyoti Borkakoty (0000-0002-6922-4198, a Regional Medical Research Centre, Northeast Region (Indian Council of Medical Research) , P.O. Box-105, Dibrugarh , 786001 , Assam , India), Hiranya Kumar Das (a Regional Medical Research Centre, Northeast Region (Indian Council of Medical Research) , P.O. Box-105, Dibrugarh , 786001 , Assam , India), Pradeep Kumar Chelleng (a Regional Medical Research Centre, Northeast Region (Indian Council of Medical Research) , P.O. Box-105, Dibrugarh , 786001 , Assam , India)
Year2009
Volume21
Issue11
Pages1420-1424
Publication date2009-11-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540120902862584
PMID20024719
OpenAlexW1976999181
LanguageEN
Citations received6
References cited7

Injection drug users (IDUs) and their associated risk behavior are responsible for driving the human immunodeficiency virus (HIV) epidemic in northeast India. So a group of IDUs from two northeastern states (Mizoram and Nagaland) of India were studied to find the prevalence of HIV, co-infection with hepatitis C virus (HCV), hepatitis B virus (HBV), and associated risk behaviors. Out of the 400 IDUs enrolled, 398 consented for HIV, HCV, and hepatitis B surface antigen (HbsAg) test. Of them, 10.8% were HIV-1 antibody positive, 47.8% had HCV antibody, and 3.8% had detectable HBsAg. Among the HIV infected subjects, 79.1% were co-infected with HCV and 6.9% had triple infection. Heroin users showed a higher association with HIV (OR = 7.3, 95% CI: 2.5-21.5, p=0.0003) and HCV infection (OR = 7.6, 95% CI: 3.5-16.6, p<0.0001) than Spasmo-proxyvon (dextropropoxyphene, a synthetic opiod analgesic). In summary, apart from the known risk variables among IDUs, type of injecting drugs also influences the HIV/HCV transmission pattern among the IDUs

HBsAg · Hepatitis B · Hepatitis B virus · Hepatitis C · Hepatitis C virus · Virus · Hepatitis B Virus Studies · Hepatitis C virus research · HIV, Drug Use, Sexual Risk · Medicine · Immunology · Internal Medicine · Virology

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