Association of caregiver quality of care with neurocognitive outcomes in HIV-affected children aged 2–5 years in Uganda

Dados Bibliográficos

ID19440503
AutoresJeffrey Ba (0000-0002-5192-628X, Johns Hopkins University, autor correspondente), Judith K Bass, Noeline Nakasujja (0000-0002-8163-4376, Makerere University), Itziar Familiar‐Lopez (Michigan State University), Itziar Familiar-Lopez, Alla Sikorskii (0000-0002-4121-1627, Michigan State University), Sarah M Murray (0000-0002-4976-9713, Johns Hopkins University), Robert O Opoka (0000-0003-3240-2058, Makerere University), Robert Opoka, Jura L Augustinavicius (0000-0001-6763-2027, Johns Hopkins University), Jura Augustinavicius, Michael J Boivin (0000-0002-0097-1777, Michigan State University)
Ano2016
Volume28
Fascículosup1
Páginas76-83
Data de publicação2016-03-24
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoAIDS Care (JOURNAL)
Identificadores do periódicoISSN: 0954-0121 • E-ISSN: 1360-0451
EditoraInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2016.1146215
PMID26888568
OpenAlexW2284191358
IdiomaEN
Citações recebidas13
Referências citadas36

Children affected by HIV are at increased risk of developmental and neuropsychological disturbances due to direct effects of HIV on the brain and direct effects associated with living in poverty. Caregivers can play an important role, through quality caregiving, in mitigating the negative effect of these stressors. This study used baseline data from an ongoing caregiver training intervention trial to evaluate the association between quality of caregiver-child interactions and neurocognitive outcomes in rural HIV-infected and HIV-exposed but uninfected children in Uganda. We also assessed the extent to which caregiver distress moderated this relationship. Data on 329 caregiver-child dyads were collected between March 2012 and July 2014, when the children were between 2 and 5 years of age. Child outcomes include the Mullen Scales of Early Learning to assess general cognitive ability and the Color Object Association Test to assess immediate memory and total recall. Caregiving quality was assessed using the Home Observation for the Measurement of the Environment (HOME) total and subscale scores. Caregiver distress was assessed using the Hopkins Symptom Checklist. General linear regression models assessed the association between the HOME total and subscale scores and child outcomes, with interaction terms used to test moderation by caregiver distress. Total HOME scores were positively and significantly associated with Mullen scores of cognitive ability; HOME acceptance subscale scores were positively and significantly associated with immediate recall scores. No other associations were statistically significant. As hypothesized, there is a strong association between the HOME and Mullen scores of cognitive ability in our study population, such that children who were assessed as living in environments with more stimulation also presented with a higher level of general neurocognitive development. Our results support the view of program guidance for HIV-affected children that suggest family-oriented care with emphasis on parent-child relationships for optimal child development

Child Behavior Checklist · Cognition · Neurocognitive · Population · Psychiatry · Child Nutrition and Water Access · Clinical Psychology · Maternal Mental Health During Pregnancy and Postpartum · Medicine · Poverty, Education, and Child Welfare · Psychology