Effect of changing antiretroviral treatment eligibility criteria on patient load in Kampala, Uganda
Bibliographic Data
| ID | 19440686 |
|---|---|
| Authors | Joseph Konde-Lule (Makerere University, corresponding author), Fred Makumbi (Makerere University), Nadine Pakker, Nadine G Pakker (Amsterdam UMC Location University of Amsterdam), Asad Muyinda (0000-0003-4376-6527, Makerere University), Mesach Mubiru (Kampala Capital City Authority), Frank Cobelens (0000-0002-4367-1133, Amsterdam UMC Location University of Amsterdam), Frank G J Cobelens |
| Year | 2011 |
| Volume | 23 |
| Issue | 1 |
| Pages | 35-41 |
| Publication date | 2011-01-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | AIDS Care (JOURNAL) |
| Journal identifiers | ISSN: 0954-0121 • E-ISSN: 1360-0451 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/09540121.2010.498869 |
| PMID | 20924829 |
| OpenAlex | W2092787574 |
| Language | EN |
| Citations received | 1 |
| References cited | 14 |
In many resource-poor countries, CD4 count thresholds of eligibility for antiretroviral treatment (ART) were initially low (<200 cells/mm(3)) but are now being increased to improve patient survival and to reduce HIV transmission. There are few quantitative data on the effect of such increases on the demand for ART. The objective of this study was to measure HIV prevalence and the proportion of HIV-positives eligible for antiretroviral therapy at different CD4 cut-off levels among users of public health care services in Kampala, Uganda. We recruited 1200 adults from three primary care clinics in Kampala, including equal numbers of family planning (FP) clients, pregnant women, adult patients with any complaint, and persons seeking HIV counseling and testing. All participants were screened for HIV and those positive had a CD4 count done. HIV prevalence in all patients was 16.9% (203/1200). ART eligibility based on CD4 counts significantly increased from 36% at a 200 cells/mm(3) cut-off to 44% at 250 cells and to 57% at 350 cells cut-off (p for χ(2) trend<0.001). We concluded that changing cut-off levels to higher CD4 counts will significantly increase patient load in Kampala's primary care clinics, but a phased implementation should minimize negative effects on quality of care
Antiretroviral therapy · Antiretroviral treatment · Developing country · Family medicine · Health care · Public health · Viral load · Young adult · HIV Research and Treatment · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Nursing · Internal Medicine
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,07 |
| Citation span | 2012 - 2012 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |