Health and sociodemographic factors associated with low muscle strength, muscle mass, and physical performance among people living with HIV
Bibliographic Data
| ID | 19440748 |
|---|---|
| Authors | Vitor H F Oliveira (0000-0002-2273-1408, University of Washington, corresponding author), Allison R Webel (0000-0002-7538-5780, University of Washington), Ana Lucia Borsari, José David G Cárdenas (Universidade Estadual de Londrina), Rafael Deminice (0000-0002-9246-1079, Universidade Estadual de Londrina) |
| Year | 2023 |
| Volume | 35 |
| Issue | 12 |
| Pages | 1863-1873 |
| Publication date | 2023-12-02 |
| Open Access | No |
| Type | ARTICLE |
| Venue | AIDS Care (JOURNAL) |
| Journal identifiers | ISSN: 0954-0121 • E-ISSN: 1360-0451 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/09540121.2022.2147482 |
| PMID | 36404290 |
| OpenAlex | W4309443580 |
| Language | EN |
| References cited | 52 |
This study examined the factors associated with low muscle strength, muscle mass, and physical performance in 331 people living with HIV. Participants completed handgrip as a strength measure, appendicular skeletal muscle mass using bioimpedance analysis, and chair rise was a physical performance measure. Multivariate logistic regression was used to analyze the association between low values on these measures with sociodemographic, HIV-related factors, and comorbidities. Higher body mass index (BMI) (OR = 0.91; CI = 0.86-0.97) and higher CD4/CD8 ratio (OR = 0.38; 95% CI = 0.18-0.82) were associated with decreased likelihood of low handgrip strength. Being non-employed (OR = 2.08; 95% CI = 1.07-4.06), having hypertension (OR = 2.27; 95% CI = 1.13-4.54) and rheumatism (OR = 5.46; 95% CI = 1.68-17.74) increased the chance of low handgrip strength. Higher BMI (OR = 0.43; 95% CI = 0.34-0.56), CD4/CD8 ratio (OR = 0.29; 95% CI = 0.09-0.93), and bioimpedance phase angle (OR = 0.22; 95% CI = 0.12-0.40) were associated with decreased likelihood of low muscle mass. Lastly, having less than eight years of education (OR = 1.87; 95% CI = 1.02-3.41) and being non-employed (OR = 8.18; 95% CI = 3.09-21.61) increased the chance of low chair stand performance. In addition, higher CD4 + lymphocytes count (OR = 0.99; 95% CI = 0.99-0.99) was associated with a decreased likelihood of low chair stand performance. In conclusion, specific and non-specific HIV-related factors are associated with low handgrip strength, low muscle mass, and/or low chair stand performance
Body mass index · Grip strength · Logistic regression · Muscle mass · Physical therapy · Sarcopenia · Body Composition Measurement Techniques · HIV-related health complications and treatments · Medicine · Nutrition and Health in Aging · Internal Medicine
| Highly cited | No |
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