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“It’s about my life”

Facilitators of and barriers to isoniazid preventive therapy completion among people living with HIV in rural South Africa

Dados Bibliográficos

ID19440901
AutoresKaren B Jacobson (0000-0003-3050-4595, Icahn School of Medicine at Mount Sinai, autor correspondente), Linda Niccolai (Department of Epidemiology of Microbial Diseases, Yale University School of Public Health, New Haven, USA), Linda M Niccolai (0000-0003-2969-3157, Yale University), Nonhle Mtungwa (0000-0001-9958-3864, Research Department, Philanjalo Care Centre, Tugela Ferry, South Africa), Anthony P Moll (Church of Scotland Hospital, Tugela Ferry, South Africa), Sheela V Shenoi (0000-0001-7654-4344, Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, Yale University School of Medicine, New Haven, USA)
Ano2017
Volume29
Fascículo7
Páginas936-942
Data de publicação2017-07-03
Peer ReviewedSim
Open AccessNão
TipoARTICLE
PeriódicoAIDS Care (JOURNAL)
Identificadores do periódicoISSN: 0954-0121 • E-ISSN: 1360-0451
EditoraInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2017.1283390
PMID28147705
OpenAlexW2585972988
IdiomaEN
Citações recebidas9
Referências citadas17

Despite the recent rollout of Isoniazid Preventive Therapy (IPT) to prevent TB in people living with HIV in South Africa, adherence and completion rates are low. To explore barriers to IPT completion in rural KwaZulu-Natal, South Africa, we conducted individual semi-structured interviews among 30 HIV patients who had completed or defaulted IPT. Interview transcripts were analyzed according to the framework method of qualitative analysis. Facilitators of IPT completion included knowledge of TB and IPT, accepting one's HIV diagnosis, viewing IPT as similar to antiretroviral therapy, having social support in the community and the clinic, trust in the healthcare system, and desire for health preservation. Barriers included misunderstanding of IPT's preventive role in the absence of symptoms, inefficient health service delivery, ineffective communication with healthcare workers, financial burden of transport to clinic and lost wages, and competing priorities. HIV-related stigma was not identified as a significant barrier to IPT completion, and participants felt confident in their ability to manage stigma, for example by pretending their medications were for unrelated conditions. Completers were more comfortable communicating with health care workers than were defaulters. Efforts to facilitate successful IPT completion must include appropriate counseling and education for individual patients and addressing inefficiencies within the health care system in order to minimize patients' financial and logistical burden. These patient-level and structural changes are necessary for IPT to successfully reduce TB incidence in this resource-limited setting

Business · Family medicine · Health care · Health education · Psychiatry · Public health · Qualitative research · Service delivery framework · Social stigma · HIV/AIDS Research and Interventions · Medicine · Nursing · Pneumocystis jirovecii pneumonia detection and treatment · Tuberculosis Research and Epidemiology

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    Open Access•Carlo Foppiano Palacios, Anthony P Moll et al.•BMC Public Health•2025

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    Open Access•Clay Roscoe, Chris Lockhart et al.•BMC Public Health•2020

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    Sarah Norton, Anthony P Moll et al.•African Journal of AIDS Research•2023

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    Khai Hoan Tram, Florence Mwangwa et al.•AIDS Care•2020

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Obras citantes distintas9
Citações por ano1,29
Intervalo de citações2019 - 2025 (7)
Velocidade de citaçãorecent
Altamente citadoNão
Tipos de citaçãoNeutras: 9
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