Correlates of antiretroviral coverage for prevention of mother-to-child transmission of HIV in sub-Saharan Africa

Bibliographic Data

ID19440941
AuthorsBabayemi O Olakunde (0000-0002-0864-6901, National Agency for the Control of AIDS, Abuja, Nigeria, corresponding author), Daniel A Adeyinka (0000-0003-1855-6878, National AIDS & STIs Control Programme, Federal Ministry of Health, Abuja, Nigeria), Olubunmi A Olakunde (Ondo State Primary Health Care Development Board, Akure, Nigeria), Chamberline E Ozigbu (0000-0001-7552-7905, National AIDS & STIs Control Programme, Federal Ministry of Health, Abuja, Nigeria), Chinwendu Daniel Ndukwe (National Agency for the Control of AIDS), Tolu Oladele (National Agency for the Control of AIDS, Abuja, Nigeria), Sabastine Wakdok (0000-0003-4371-0320, National Agency for the Control of AIDS, Abuja, Nigeria), Samuel Udemezue (National Agency for the Control of AIDS, Abuja, Nigeria), Echezona E Ezeanolue (0000-0002-6294-9479, University of Nigeria)
Year2019
Volume31
Issue10
Pages1255-1260
Publication date2019-10-03
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2019.1587364
PMID30829049
OpenAlexW2919355615
LanguageEN
Citations received1
References cited24

Antiretroviral (ARV) drugs are effective in the prevention of mother-to-child transmission of HIV (PMTCT), however many sub-Saharan African countries are yet to achieve universal ARV coverage among pregnant women living with HIV. This study examined factors associated with ARV coverage for PMTCT in 41 sub-Saharan Africa countries. Country-level aggregated data were obtained from the Joint United Nations Programme on HIV/AIDS, World Health Organization, and United Nations Children’s Fund. Using Spearman’s rho and point-biserial correlation, we conducted bivariate analyses between ARV coverage for PMTCT and the following variables: stigma, antenatal care (ANC) uptake, institutional delivery, community delivery of ARV drugs, number of HIV testing and counselling (HTC) facilities, and density of skilled health workers. We also performed a multivariate median regression with the significant correlates. P < .05 was considered statistically significant for all the tests. The median ARV coverage for PMTCT was 76% (IQR: 55–85%). ARV coverage for PMTCT was significantly associated with HTC facilities (r = 0.46, p = .004), institutional delivery (r = 0.48, p = .002), ANC uptake: at least one visit (r = 0.54, p = .001), and stigma (r=−0.52, p = .003). In the multivariate analysis, only stigma remained statistically significant (β = −0.6, 95% CI = −1.13, −0.07, p = .03). To eliminate perinatal transmission of HIV in sub-Saharan Africa, interventions that will address stigma-related barriers to uptake of PMTCT services are needed. More research on country-specific population-level correlates of ARV coverage for PMTCT is recommended

Developing country · Environmental health · Family medicine · Multivariate analysis · Population · Psychiatry · Psychological intervention · Adolescent Sexual and Reproductive Health · Demography · Global Maternal and Child Health · HIV/AIDS Research and Interventions · Medicine · Nursing · Internal Medicine

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