The Repeatable Battery for the Assessment of Neuropsychological Status as a screening strategy for HIV-Associated Neurocognitive Disorders
Bibliographic Data
| ID | 19441470 |
|---|---|
| Authors | Diego Costaggiu (University of Cagliari), Elisa Pinna (University of Cagliari), Luca Serchisu (University of Cagliari), Doris Barcellona (0000-0002-0823-3357, University of Cagliari), Paola Piano (University of Cagliari), Francesco Perna (0000-0002-2177-1184, University of Cagliari), Francesco Ortu (University of Cagliari), Francesco Marongiu (0000-0001-7277-2868, University of Cagliari), Antonella Mandas (0000-0003-3893-1794, University of Cagliari, corresponding author) |
| Year | 2021 |
| Volume | 33 |
| Issue | 3 |
| Pages | 357-363 |
| Publication date | 2021-03-04 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | AIDS Care (JOURNAL) |
| Journal identifiers | ISSN: 0954-0121 • E-ISSN: 1360-0451 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/09540121.2020.1742859 |
| PMID | 32183560 |
| OpenAlex | W3010690573 |
| Language | EN |
| Citations received | 1 |
| References cited | 36 |
HIV-infected people are at risk for neurocognitive impairment (HIV-Associated Neurocognitive Disorders – HAND). To evaluate whether the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), a widely used neurocognitive screening tool, could be a valid instrument for HAND identification, we evaluated 166 HIV-infected subjects. Our results showed that 96 (57.8%) HIV-infected scored RBANS Total Index Score <85 (at least one SD below the normal), 12 (7.2%) of them scored RBANS Total Index Score <70 (at least 2 SD below the normal, indicating a possible HIV-Associated Dementia). The more compromised areas were Immediate and Delayed Memory, and Attention. In the group with RBANS Total Index Score <85, there were significantly lower scores of Mini Mental State Examination (P = 0.0008), Clock Drawing Test (P = 0.0015) and higher score of Geriatric Depression Scale (P = 0.02) compared to the RBANS Total Index Score ≥85 group. Using a stepwise logistic regression, considering RBANS Total Index Score as dependent variable, we found a positive interaction with tenofovir/emtricitabine assumption (P = 0.027), Clock Drawing Test (P = 0.0125) and educational level (P = 0.0054). Being the viro-immunological markers not capable of predicting cognitive decline in HIV-infected individuals, our data suggest that RBANS may be a valid tool for the early identification of HIV-related cognitive impairment
Antiretroviral therapy · Cognition · Dementia · Depressive symptoms · Emtricitabine · Geriatric Depression Scale · Logistic regression · Neurocognitive · Neuropsychology · Psychiatry · Repeatable Battery for the Assessment of Neuropsychological Status · Viral load · Clinical Psychology · HIV Research and Treatment · HIV-related health complications and treatments · HIV/AIDS Research and Interventions · Medicine · Immunology · Internal Medicine
The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)
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Updated research nosology for HIV-associated neurocognitive disorders
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Assessment of Older People
| Unique citing works | 1 |
|---|---|
| Citations per year | 0.25 |
| Citation span | 2022 - 2022 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |