Challenges to PrEP use and perceptions of urine tenofovir adherence monitoring reported by individuals on PrEP
Bibliographic Data
| ID | 19441867 |
|---|---|
| Authors | Travis Hunt (Sidney Kimmel Medical College, Thomas Jefferson University, corresponding author), Linden Lalley-Chareczko (0000-0003-0699-8345, Philadelphia Fight), Giffin Daughtridge (UrSure Inc.), Meghan Swyryn (Philadelphia Fight), Helen Koenig (Philadelphia Fight) |
| Year | 2019 |
| Volume | 31 |
| Issue | 10 |
| Pages | 1203-1206 |
| Publication date | 2019-10-03 |
| Open Access | No |
| Type | ARTICLE |
| Venue | AIDS Care (JOURNAL) |
| Journal identifiers | ISSN: 0954-0121 • E-ISSN: 1360-0451 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/09540121.2019.1587369 |
| PMID | 30821473 |
| OpenAlex | W2919645266 |
| Language | EN |
| Citations received | 8 |
| References cited | 10 |
Maximizing the impact of HIV pre-exposure prophylaxis (PrEP) requires optimizing access and adherence for those at risk of contracting HIV. This study examined challenges to the processes of accessing and adhering to PrEP encountered by participants from a large, U.S. urban clinical center and assessed the utility of objectively monitoring PrEP adherence via urine. Most participants (65%) reported starting PrEP within 1-3 months of hearing about it, although 35% of participants encountered a provider unwilling to prescribe PrEP. Self-reported adherence was high among this population, with remembering to take the medication reported as the major barrier to adherence (44%) rather than cost or stigma. Urine tenofovir (TFV) monitoring was highly acceptable to this population, and participants indicated greater willingness to undergo urine monitoring every 3 months compared to finger prick (dried blood spot), phlebotomy, or hair follicle testing. These findings highlight the importance of focusing efforts toward reducing obstacles to PrEP use and support the use of urine TFV adherence monitoring as a marker of PrEP adherence
Environmental health · Family medicine · Intensive care medicine · Men who have sex with men · Phlebotomy · Population · Pre-exposure prophylaxis · Tenofovir · Urine · HIV Research and Treatment · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Internal Medicine
“Whatever is in the ARVs, is Also in the PrEP” Challenges Associated With Oral Pre-exposure Prophylaxis Use Among Female Sex Workers in South Africa
Barriers to Same-Day Pre-exposure Prophylaxis (PrEP) Implementation in Federally Funded HIV Clinics Within High-Burden Areas of the U.S
Exploration of Pregnant and Breastfeeding Women’s Acceptability of Rapid Point-of-Care Urine Testing Within Antenatal and Postnatal Care, and Its Perceived Impact on PrEP Adherence When Paired with PrEP Biofeedback Adherence Counselling in Cape Town, South Africa
Reddit on PrEP
Client-Centered Adherence Counseling with Adherence Measurement Feedback to Support Use of the Dapivirine Ring in MTN-025 (The Hope Study)
Point-of-Care Test for Assessing Tenofovir Adherence
Perspectives of people living with HIV and health workers about a point-of-care adherence assay
Acceptability and feasibility of a urine-based tenofovir adherence assay for monitoring and providing feedback on PrEP adherence in Kenya
| Citations per year | 1.33 |
|---|---|
| Citation span | 2020 - 2026 (7) |
| Highly cited | No |