Alcohol dependence and CD4 cell count
Is there a relationship
Bibliographic Data
| ID | 19442469 |
|---|---|
| Authors | André Malbergier (0000-0001-6093-8381, Department of Psychiatry, Medical School, University of São Paulo, São Paulo, Brazil, corresponding author), Ricardo Abrantes Do Amaral (0000-0002-1144-1229, Department of Psychiatry, Medical School, University of São Paulo, São Paulo, Brazil), Luciana Donola Cardoso (Universidade de São Paulo) |
| Year | 2015 |
| Volume | 27 |
| Issue | 1 |
| Pages | 54-58 |
| Publication date | 2015-01-02 |
| Open Access | No |
| Type | ARTICLE |
| Venue | AIDS Care (JOURNAL) |
| Journal identifiers | ISSN: 0954-0121 • E-ISSN: 1360-0451 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/09540121.2014.947235 |
| PMID | 25179410 |
| OpenAlex | W2094729750 |
| Language | EN |
| Citations received | 5 |
| References cited | 14 |
Alcohol and other drugs use seem to be common among people infected with HIV on antiretroviral treatment (ART). Their effects on HIV progression is still in debate. This study aimed to assess the association between alcohol and drug use and an HIV disease progression biomarker (CD4 cell count) among patients on ART. A cross-sectional study was carried out at an HIV treatment center affiliated with Medical School of the University of São Paulo, Brazil. Four hundred and thirty-eight HIV-positive patients on ART were interviewed by trained psychiatrists and psychologists using the following instruments: Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Alcohol Use Disorders Identification Test (AUDIT), 17-item Hamilton Rating Scale for Depression, and the Simplified Medication Adherence Questionnaire (SMAQ). In the previous month, 219 (50%) and 41 (9.3%) patients reported use of alcohol and illicit drugs, respectively. Fifty patients (12.6%) were classified as having harmful alcohol use by AUDIT. According to SCID-I, 80 patients (18.3%) were alcohol abusers, 24 (5.5%) alcohol dependents, and 21 (4.2%) had a current depressive disorder. Almost 73% (n = 319-72.8%) of the patients were adherent to ART. Alcohol dependents were nine times (p < 0.01) more likely to have CD4 cell count ≤200/mm(3), and this association was independent of ART adherence. In conclusion, alcohol dependence seems to be associated with low CD4 cell count in HIV-positive patients. Based on these data, HIV health care workers should always assess alcohol consumption in the treatment setting, and patients should be advised that alcohol dependence may be linked to low CD4
Alcohol · Alcohol abuse · Alcohol consumption · Alcohol dependence · Alcohol Use Disorders Identification Test · Family medicine · Psychiatry · HIV-related health complications and treatments · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Internal Medicine
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| Citations per year | 0.45 |
|---|---|
| Citation span | 2015 - 2020 (6) |
| Highly cited | No |