Club drugs and alcohol abuse predicted dropout and poor adherence among methadone maintenance treatment patients in Guangzhou, China

Bibliographic Data

ID19442689
AuthorsDi Liu (0000-0002-6015-1965, Sun Yat-sen University), Jing Gu (0000-0002-4035-9072, Sun Yat-sen University, corresponding author), Huifang Xu (0000-0002-9492-5690, Guangzhou Center for Disease Control and Prevention), Chun Hao (0000-0002-9881-6504, Sun Yat-sen University), Mingxu Jiao (Sun Yat-sen University), Xiao Zhang (0000-0002-0342-3282, Sun Yat-sen University), Zhang Xiao (0000-0002-5682-9876), Yuteng Zhao (Guangzhou Center for Disease Control and Prevention), Babbitt Andrew (Sun Yat-sen University), Yuantao Hao (0000-0001-8024-5312, Sun Yat-sen University)
Year2017
Volume29
Issue4
Pages458-463
Publication date2017-04-03
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2016.1259452
PMID27903083
OpenAlexW2558734034
LanguageEN
Citations received4
References cited24

Club drugs and alcohol abuse are prevalent among methadone maintenance treatment (MMT) patients. However, little is known about the association between these abuse and treatment outcomes among MMT patients. The aim of this study was to examine the prevalence of club drugs and alcohol abuse among MMT patients and to investigate the associations between these abuse and treatment outcomes - dropout and poor adherence. In this one-year cohort study conducting in Guangzhou, China, data including background characteristics, club drugs use in the last six months, alcohol use history and treatment-related information was collected. Cox regression analyses and log-binomial regression analyses were applied to identify the associations between these abuse and dropout and poor adherence, respectively. Thirty-seven participants (9.2%) admitted to the use of at least one type of club drugs in the last six months and 88 (21.9%) were identified as alcohol abusers. Of all participants, 21.0% had dropped out of treatment and 27.7% exhibited poor adherence during the study period. Adjusting for significant background variables, use of at least one type of club drugs [hazards ratio (HR) = 1.90, 95% confidence interval (CI) = 1.01-3.56] and use of methamphetamine in the last six months (HR = 2.26, 95% CI = 1.15-4.43) significantly predicted dropout. Frequency of having six or more drinks on one drinking occasion when drinking [relative risk (RR) = 1.87, 95% CI = 1.16-2.95] significantly predicted poor adherence. Our findings indicated that club drugs and alcohol abuse predicted dropout and poor adherence among MMT patients. Early identification and intervention for the abuse should be taken into consideration when developing interventions tailored to improve treatment outcomes among MMT patients

Alcohol abuse · China · Club · Geography · Methadone · Methadone maintenance · Psychiatry · Substance abuse · HIV, Drug Use, Sexual Risk · Medicine · Opioid Use Disorder Treatment · Psychology · Substance Abuse Treatment and Outcomes

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