Skip to main content

ETHNOS_APP

Home • Search • Journals • List 0

Antiretroviral therapy based HIV prevention targeting young women who sell sex

A mixed method approach to understand the implementation of PrEP in a rural area of KwaZulu-Natal, South Africa

Bibliographic Data

ID19442987
AuthorsNatsayi Chimbindi (0000-0003-3125-978X, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa, corresponding author), Nondumiso Mthiyane (0000-0002-9881-7267, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa), Thembelihle Zuma (0000-0002-8374-2354, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa), Kathy Baisley (0000-0003-1849-6625, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa), Deenan Pillay (0000-0003-3640-2573, Institute for Global Health, University College London (UCL), London, UK), Nicky Mcgrath (0000-0002-1039-0159, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa), Guy Harling (0000-0001-6604-491X, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa), Lorraine Sherr (0000-0002-5902-8011, Institute for Global Health, University College London (UCL), London, UK), Isolde Birdthistle (0000-0001-5742-6588, London School of Hygiene & Tropical Medicine), Sian Floyd (0000-0002-8615-7601, London School of Hygiene & Tropical Medicine), Jaco Dreyer (0000-0002-9966-5744, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa), Sarah Nakasone (0000-0003-1720-2365, University of Chicago, Chicago, IL, USA), Janet Seeley (0000-0002-0583-5272, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa), M Shahmanesh (0000-0001-7129-8535, Africa Health Research Institute (AHRI), KwaZulu-Natal, South Africa)
Year2022
Volume34
Issue2
Pages232-240
Publication date2022-02-01
Open AccessYes
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2021.1902933
PMID33769156
OpenAlexW3137011600
LanguageEN
Citations received9
References cited25

Pre-Exposure Prophylaxis (PrEP) is a potential game-changer for HIV. We used PrEP introduction for Young Women Who Sell Sex (YWSS) in a rural South Africa district to understand community norms and PrEP coverage in YWSS. Between 2017 and 2018, we measured awareness and uptake of PrEP in a representative cohort of 2184 Adolescent Girls and Young Women (AGYW) aged 13-22. We conducted group discussions with young people and community members (19); key informant interviews (9), in-depth interviews with 15-24 year-olds (58) and providers (33). Interviews were analysed using thematic analysis. PrEP awareness increased from 2% to 9%. Among 965 AGYW sexually-active by 2018, 13.4% (95%CI: 11.4%-15.7%) reported transactional sex and 10.6% (95%CI: 8.85-12.7%) sex for money. Of the 194 YWSS, 21 were aware of PrEP, but none had used it. Youth were enthusiastic about PrEP as tool for HIV prevention; whilst older community members were cautious about a technology they had limited experience with but could benefit select groups. Teachers and healthcare providers were concerned that PrEP would lower personal responsibility for sexual health. In conclusion, the narrow and limited introduction of PrEP to YWSS reduced the accessibility and reach. Introducing PrEP as part of sexual healthcare may improve demand and access for YWSS

Cohort · Environmental health · Family medicine · Focus group · Men who have sex with men · Population · Pre-exposure prophylaxis · Qualitative research · Sociology · Thematic analysis · Transactional sex · Adolescent Sexual and Reproductive Health · HIV/AIDS Research and Interventions · Medicine · Psychology · Sex work and related issues

  • Lives Interrupted

    Open Access•Thembelihle Zuma, Rachel King et al.•Progress in Development Studies•2021

  • Thetha Nami ngithethe nawe (Let’s Talk)

    Open Access•Jacob Busang, Thembelihle Zuma et al.•BMC Public Health•2023

  • Empowering women at risk

    Open Access•Ndumiso Tshuma, Daniel N Elakpa et al.•BMC Public Health•2025

  • Long-acting HIV pre-exposure prophylaxis integrated with community-based sexual and reproductive health services in South Africa (Lapis)

    Open Access•Jacob Busang, Thembelihle Zuma et al.•BMC Public Health•2026

  • Evaluating Motivational Interviewing and Peer Adherence Support as Strategies to Improve Oral PrEP Adherence among HIV-Negative Adults in KwaZulu-Natal, South Africa

    Open Access•Sherishka Dhindayal, Sanele Mbeje et al.•AIDS and Behavior•2026

  • Interventions to increase the uptake and continuation of pre-exposure prophylaxis (PrEP) by adolescent girls and young women at high risk of HIV in low-income and middle-income countries

    Open Access•Obinna Ikechukwu Ekwunife, Izuchukwu Loveth Ejie et al.•BMJ Global Health•2022

  • Factors Associated with Usage of Oral-PrEP among Female Sex Workers in Nairobi, Kenya, Assessed by Self-Report and a Point-of-Care Urine Tenofovir Immunoassay

    Open Access•Pooja Shah, Matthew A Spinelli et al.•AIDS and Behavior•2024

  • The sexual and reproductive health needs of school-going young people in the context of Covid-19 in rural KwaZulu-Natal, South Africa

    Open Access•Natsayi Chimbindi, Ursula Ngema et al.•African Journal of AIDS Research•2022

  • Motivators for oral PrEP uptake and adherence in the eThekwini municipality, KwaZulu-Natal

    Jyotika Basdav, Poovendhree Reddy et al.•AIDS Care•2023

  • Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy

    Alec Rodger, Alison J Rodger et al.•JAMA•2016

  • Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women

    Jared M Baeten, Deborah Donnell et al.•New England Journal of Medicine•2012

  • Transactional sex and risk for HIV infection in sub‐Saharan Africa

    Open Access•Joyce Wamoyi, Kirsten Stobeanau et al.•Journal of the International AIDS…•2016

  • Preexposure Prophylaxis for HIV Infection among African Women

    Lut Van Damme, Amy Corneli et al.•New England Journal of Medicine•2012

  • Access as a policy-relevant concept in low- and middle-income countries

    Open Access•Di Mcintyre, Michael Thiede et al.•Health Economics Policy and Law•2009

  • Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD)

    Open Access•Sheena McCormack, D Dunn et al.•The Lancet•2016

  • Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

    Jeanne Marrazzo, Jeanne M Marrazzo et al.•New England Journal of Medicine•2015

  • PrEP Stigma

    Open Access•Sarit A Golub•Current HIV/AIDS Reports•2018

  • Evaluating the impact of the DREAMS partnership to reduce HIV incidence among adolescent girls and young women in four settings

    Open Access•Isolde Birdthistle, B Schaffnit et al.•BMC Public Health•2018

  • Understanding Demand for PrEP and Early Experiences of PrEP Use Among Young Adults in Rural Kenya and Uganda

    Open Access•Carol S Camlin, Catherine A Koss et al.•AIDS and Behavior•2020

  • Experiences with HPTN 067/Adapt Study-Provided Open-Label PrEP Among Women in Cape Town

    Open Access•K Rivet Amico, Melissa Wallace et al.•AIDS and Behavior•2016

  • Revisiting the understanding of “transactional sex” in sub-Saharan Africa

    Open Access•Kirsten Stoebenau, Lori Heise et al.•Social Science & Medicine•2016

  • Transactional sex among women in Soweto, South Africa

    Open Access•Kristin Dunkle, Kristin L Dunkle et al.•Social Science & Medicine•2004

Citations per year1.8
Citation span2021 - 2026 (6)
Highly citedNo

Tools

Open DOIOpen Access
Ethnos_APP • Open Source Project • MIT License • Frontend v2.0.0 • Privacy and Cookies • API Documentation: api.ethnos.app/docs • API Source Code: GitHub • DOI: 10.5281/zenodo.17049435 • Frontend Source Code: GitHub • DOI: 10.5281/zenodo.17050053 • cruz.rio.br • Expectantes Misericordiae