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Methodologies used in studies examining substance abuse, violence and HIV/Aids (Sava) constructs using a syndemic framework

A scoping review

Bibliographic Data

ID19444196
AuthorsJennifer V Chavez (0000-0002-4576-9898, University of Miami, corresponding author), Piao Wang (0000-0001-9662-8094, University of Miami), Michaela E Larson (0000-0003-1821-1239, University of Miami), Vicky Vazquez (0000-0003-3209-397X, Florida International University), Mario De La Rosa (0000-0001-6503-6029, Florida International University), Victoria Behar‐zusman (0000-0002-8732-0116, University of Miami)
Year2023
Volume35
Issue11
Pages1708-1715
Publication date2023-11-02
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2023.2176426
PMID36942772
OpenAlexW4328048567
LanguageEN
Citations received3
References cited30

The syndemic theoretical framework has been used in health disparities research to explain several co-occurring epidemics, particularly in populations facing disparate health conditions. A prominent example of this is seen in Singer's Substance Abuse, Violence and HIV/AIDS (SAVA) syndemic theory. However, even though numerous studies support some of the theoretical underpinnings of the SAVA syndemic, the empirical applications of the theory remain methodologically underdeveloped. The current review was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review (PRISMA-ScR), to present the state of the science of methodologies examining SAVA constructs using the syndemic framework. Seven bibliographic databases were searched with no language or date restrictions. Studies were synthesized by author, year of publication, study location, total sample size, study population, SAVA outcomes, analytic method of SAVA measurement, intervention type, level of influence, disease interaction and concentration, main findings of the study, and possible future areas of research. Our search yielded a total of 967 articles, and 123 were included in the review. Methodologic and statistical innovation is needed to elevate the impact of syndemic theory for elucidating the synergistic effects of determinants leading to health disparities

Empirical research · Environmental health · Family medicine · Poison control · Psychiatry · Substance abuse · Syndemic · Adolescent Sexual and Reproductive Health · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Mathematics · Medicine · Psychology

  • A Syndemic Clustering of Adversities on Suicide Risk among YMSM Living with HIV in Bangkok

    Open Access•Doug H Cheung, Worawalan Waratworawan et al.•AIDS and Behavior•2025

  • Parenting under the triple burden of violence, depression, and poor diet quality

    Open Access•Luissa Vahedi, Ilana Seff et al.•PLOS Global Public Health•2026

  • The intergenerational legacies of research disinvestment, aid retrenchment and transactional compacts on global women’s health

    Open Access•Roxanne Keynejad, Abigail M Hatcher et al.•PLOS Global Public Health•2026

  • Co-occurring epidemics, syndemics, and population health

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  • Alcohol use, drug use and alcohol‐related problems among men who have sex with men

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  • High Levels of Syndemics and Their Association with Adherence, Viral Non-suppression, and Biobehavioral Transmission Risk in Miami, a U.S. City with an HIV/Aids Epidemic

    Open Access•Tiffany R Glynn, Steven A Safren et al.•AIDS and Behavior•2019

  • Factors impacting HIV testing

    Katarzyna Bolsewicz, A Vallely et al.•AIDS Care•2015

  • Syndemics and Health Disparities

    Open Access•Alexander C Tsai, Atheendar Venkataramani•AIDS and Behavior•2015

  • Current Knowledge and Future Directions on Aging and HIV Research

    Charles A Emlet•Behavioral Medicine•2014

  • Aids and the health crisis of the U.S. urban poor; the perspective of critical medical anthropology

    Open Access•M Singer•Social Science & Medicine•1994

  • Syndemics of psychosocial problems and HIV risk

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  • Using Syndemic Theory to Understand Vulnerability to HIV Infection among Black and Latino Men in New York City

    Open Access•Patrick A Wilson, José Nanín et al.•Journal of Urban Health•2014

  • Application of Syndemic Theory to Black Men Who Have Sex with Men in the Multicenter Aids Cohort Study

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  • The National Institute on Minority Health and Health Disparities Research Framework

    Jennifer Alvidrez, Dorothy Castille et al.•American Journal of Public Health•2019

  • A Syndemic Model of Exchange Sex Among HIV-Positive Men Who Have Sex With Men

    Open Access•Suzan M Walter, Ryue Nishizawa et al.•Archives of Sexual Behavior•2020

  • Scoping studies

    Hilary Arksey, Lisa O’malley•International Journal of Social…•2005

  • Gendered syndemic of intimate partner violence, alcohol misuse, and HIV risk among peri-urban, heterosexual men in South Africa

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Citations per year3
Citation span2025 - 2026 (2)
Highly citedNo

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