Family history of cardiovascular disease and parental lifestyle behaviors are associated with offspring cardiovascular disease risk markers in childhood

Bibliographic Data

ID19459162
AuthorsDanilo R P Silva (0000-0003-3995-4795, Universidade Estadual de Londrina), Danilo R Silva (0000-0002-9989-7449, Study and Research Group in Metabolism Nutrition and Exercise—GEPEMENE, State University of Londrina—UEL Londrina Brazil), André Oliveira Werneck (0000-0002-9166-4376, Study and Research Group in Metabolism Nutrition and Exercise—GEPEMENE, State University of Londrina—UEL Londrina Brazil, corresponding author), P Collings (0000-0003-2022-5453, Bradford District Care NHS Foundation Trust), Paul J Collings (Bradford Institute for Health Research Bradford NHS Foundation Trust Bradford United Kingdom), Rômulo A Fernandes (0000-0003-1576-8090, Scientific Research Group Related to Physical Activity (GICRAF), Laboratory of Investigation in Exercise (LIVE), Department of Physical Education São Paulo State University (UNESP) Presidente Prudente Brazil), Décio Sabbatini Barbosa (0000-0002-8677-4730, Universidade Estadual de Londrina), Enio R V Ronque (0000-0003-3430-3993, Study and Research Group in Metabolism Nutrition and Exercise—GEPEMENE, State University of Londrina—UEL Londrina Brazil), Luís B Sardinha (0000-0002-6230-6027, Exercise and Health Laboratory Faculdade de Motrcidade Humana, Universidade de Lisboa Portugal), Edilson S Cyrino (0000-0001-9016-8779, Study and Research Group in Metabolism Nutrition and Exercise—GEPEMENE, State University of Londrina—UEL Londrina Brazil)
Year2017
Volume29
Issue5
Publication date2017-09-10
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Human Biology (JOURNAL)
Journal identifiersISSN: 1042-0533 • E-ISSN: 1520-6300
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajhb.22995
PMID28295804
OpenAlexW2592461842
LanguageEN
References cited12

INTRODUCTION: Cardiovascular disease risk markers have become more prevalent in childhood. To provide increased understanding of the etiology of this public health issue, we investigated associations between family characteristics with cardiovascular disease risk markers in adolescents from a developing nation. METHODS: In this cross-sectional study data for fasting glucose, lipoproteins (LDL-C and HDL-C), triglycerides, and total cholesterol were collected from 991 adolescents aged 10-17 who were recruited from public schools in Londrina city, Southern Brazil. Family history of cardiovascular disease and parental engagement in risk behavior (alcohol consumption and tobacco smoking) were collected using a self-reported parental questionnaire. Socioeconomic status, adolescent physical activity (estimated by Baecke questionnaire), self-reported tobacco and alcohol intake, and somatic maturation (age at peak height velocity) were used as covariates. Logistic regression was used for the main analyses. RESULTS: [95% CI]) were found between: (1) paternal family history of cardiovascular disease with increased likelihood of high adolescent offspring BMI (1.53 [1.01 to 2.32]) and high triglycerides (2.93 [1.04 to 8.27]); (2) maternal family history of cardiovascular disease with heightened odds of high adolescent offspring triglycerides (2.84 [1.02 to 7.91]); (3) maternal cardiovascular disease with higher odds of high fasting glucose (2.16 [1.13 to 4.14]), and (4) maternal smoking with increased odds of high LDL-C (1.78 [1.14 to 2.79]) and high total cholesterol (1.77 [1.01 to 3.10]) in adolescent offspring. CONCLUSION: Family history of cardiovascular disease and maternal tobacco smoking are related to increased cardiovascular risk in adolescents, potentially independent of their own lifestyle behaviors

Biology · Disease · Family history · Logistic regression · Obesity · Odds · Odds ratio · Offspring · Pregnancy · Birth, Development, and Health · Demography · Diabetes, Cardiovascular Risks, and Lipoproteins · Medicine · Obesity, Physical Activity, Diet · Internal Medicine

Tools

Open DOISci-Hub