Higher levels of central adiposity in healthy premenopausal women with family histories of premenopausal breast cancer

Bibliographic Data

ID19459205
AuthorsLucia Dettenborn (Technische Universität Dresden, corresponding author), Gary D James (0000-0002-3262-1448, Binghamton University), Julie A Britton (Icahn School of Medicine at Mount Sinai), Dana H Bovbjerg (0000-0001-8843-7669, Icahn School of Medicine at Mount Sinai)
Year2008
Volume20
Issue3
Pages355-358
Publication date2008-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Human Biology (JOURNAL)
Journal identifiersISSN: 1042-0533 • E-ISSN: 1520-6300
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajhb.20700
PMID18161037
OpenAlexW2060703134
LanguageEN
References cited16

Research strongly suggests that lower overall adiposity and higher central adiposity are independent risk factors for premenopausal breast cancer in the general population. We aimed to test the possibility that these factors may contribute to familial risk of premenopausal breast cancer. A convenience sample of healthy women, ages 25–49, was recruited to yield three study groups: (1) Women with first‐degree family histories of premenopausal breast cancer, operationally defined as being diagnosed prior to age 50 (Group FH n = 39); (2) Women with first‐degree family histories of postmenopausal breast cancer, operationally defined as being diagnosed at age 50 or after (Group FH ≥ 50, n = 33); and (3) Women without a history of breast cancer in first‐degree relatives (Group FH−, n = 132). Multinomial logistic regression analyses, including possible confounders, waist circumference, and BMI, revealed a lower BMI among FH

Body mass index · Breast cancer · Cancer · Confounding · Environmental health · Family history · Gynecology · Obesity · Obstetrics · Population · Waist · Breast Cancer Treatment Studies · Cancer Risks and Factors · Demography · Male Breast Health Studies · Medicine · Internal Medicine · Oncology

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